Effects of electrical stimulation of the superior ovarian nerve and the ovarian plexus nerve on the ovarian estradiol secretion rate in rats
Effects of electrical stimulation of the superior ovarian nerve and the ovarian plexus nerve on the ovarian estradiol secretion rate in rats
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DOI：
10.2170/physiolsci.rp001508
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发表时间：
2008-04-01
影响因子：
2.3
通讯作者：
Hotta, Harumi
中科院分区：
文献类型：
--
作者：
Kagitani, Fusako;Uchida, Sae;Hotta, Harumi
本实验观察了电刺激大鼠卵巢上级神经（SON）和卵巢丛神经（OPN）对卵巢雌二醇分泌的影响。发情当天麻醉大鼠，间断采集卵巢静脉血。从卵巢的雌二醇分泌率计算卵巢静脉血浆和全身动脉血浆之间的雌二醇浓度的差异，从卵巢静脉血浆的流速。无论是SON或OPN，同侧的卵巢，从卵巢静脉血收集，电刺激C-纤维在一个超大强度。在SON刺激期间，雌二醇的分泌率显著降低47 +/- 6%，但在OPN刺激期间没有显著变化。这些结果表明，通过SON到达卵巢的自主神经在卵巢雌二醇分泌中具有抑制作用。
The present experiments examined the effects of electrical stimulation of the superior ovarian nerve (SON) and the ovarian plexus nerve (OPN) on the ovarian estradiol secretion in rats. The rats were anesthetized on the day of estrus, and the ovarian venous blood was collected intermittently. The secretion rate of estradiol from the ovary was calculated from differences in the estradiol concentration between ovarian venous plasma and systemic arterial blood plasma, and from the flow rate of ovarian venous plasma. Either an SON or OPN, ipsilateral to the ovary from which ovarian venous blood was collected, was electrically stimulated at a supramaximal intensity for C-fibers. The secretion rate of estradiol was significantly decreased by 47 +/- 6% during SON stimulation, but it was not significantly changed during OPN stimulation. These results suggest that autonomic nerves, which reach the ovary via the SON, have an inhibitory role in ovarian estradiol secretion.