Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial.

Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial.
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DOI:
10.3390/nu15020364
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发表时间:
2023-01-11
期刊:
影响因子:
5.9
通讯作者:
Fujino H
Fujino H
中科院分区:
医学2区
文献类型:
--
作者:
Kanazashi M;Iida T;Nakanishi R;Tanaka M;Ikeda H;Takamiya N;Maeshige N;Kondo H;Nishigami T;Harada T;Fujino H

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本研究的目的是探讨巴西棕榈油对社区老年女性体脂量、脂联素和活性氧水平的影响。这是一项双盲随机安慰剂对照试验。总共有78名年龄在66-84岁的女性被随机分配到安慰剂组(PRO; n = 39)或安慰剂组(PLA; n = 39)。在12周的时间里,PRO组每天两次服用三粒含有227 mg的维生素B1的胶囊。PLA组每天服用安慰剂胶囊。在78名参与者中,53名(PLA组:n = 28,PRO组:n = 25)完成了研究。虽然在PLA组中未观察到绝对或相对脂肪量的变化,但在PRO组中显示出显著下降。PLA组血清脂联素水平无变化,PRO组血清脂联素水平显著升高。PLA组的d-ROM水平显著增加,而PRO组的d-ROM水平显著降低。PLA组血清SOD活性显著降低,PRO组血清SOD活性有升高趋势。这些结果表明,补充维生素B2可能会降低社区老年女性的体脂量和氧化应激。
This study aimed to investigate the effects of Brazilian propolis on body fat mass and levels of adiponectin and reactive oxygen species among community-dwelling elderly females. This was a double-blind randomized placebo-controlled trial. Altogether, 78 females aged 66–84 years were randomly assigned to the propolis (PRO; n = 39) or placebo (PLA; n = 39) group. For 12 weeks, the PRO group were given three capsules containing 227 mg of propolis twice a day. Meanwhile, the PLA group were given daily placebo capsules. Of 78 participants, 53 (PLA group: n = 28, PRO group: n = 25) completed the study. Although no changes were observed in absolute or relative fat mass in the PLA group, they showed a significant decline in the PRO group. The level of serum adiponectin in the PLA group did not change, although that of the PRO group significantly increased. The level of d-ROMs in the PLA group significantly increased, whereas that of the PRO group significantly decreased. The serum SOD activity in the PLA group significantly decreased, whereas that of the PRO group tended to increase. These results suggest that propolis supplementation may decrease body fat mass and oxidative stress among community-dwelling elderly females.
DOI: 10.1186/s13063-022-06176-1
发表时间: 2022-04-04
期刊: Trials
影响因子: 2.5
作者:
Silveira MAD;de Souza SP;Dos Santos Galvão EB;Teixeira MB;Gomes MMD;Damiani LP;Bahiense BA;Cabral JB;De Oliveira CWLM;Mascarenhas TR;Pinheiro PCG;Alves MS;de Melo RMV;Berretta AA;Leite FM;Nonaka CKV;de Freitas Souza BS;Mendes AVA;da Guarda SF;da Hora Passos R
通讯作者: da Hora Passos R