The effect of very early mobilization after stroke on psychological well-being
The effect of very early mobilization after stroke on psychological well-being
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DOI：
10.2340/16501977-0226
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发表时间：
2008-09-01
影响因子：
3.5
通讯作者：
Bernhardt, Julie
中科院分区：
文献类型：
--
作者：
Cumming, Toby B.;Collier, Janice;Bernhardt, Julie
目的：急性脑卒中患者常见的不活动有增加负性情绪症状的可能。我们评估了中风后早期活动对抑郁、焦虑和易怒水平的影响。设计：AVERT是一项随机对照试验；与标准护理组相比，非常早期活动组患者接受活动的时间更早（卒中后24小时内），并且活动频率更高。患者：纳入71例卒中确诊患者。方法：采用易怒、抑郁和焦虑（IDA）量表在多个时间点对患者进行评估。结果：在第7天，极早运动患者的抑郁程度（z=2.51, p=0.012）和焦虑程度（z=1.79, p=0.073）均低于标准护理患者（Mann-Whitney检验）。将IDA评分分为正常或抑郁，并使用后向逐步多变量logistic回归，非常早的活动与7天抑郁可能性降低相关（优势比0.14,95%，置信区间0.03-0.61;p=0.009）。结论：早期活动可减轻脑卒中患者脑卒中后7天的抑郁症状。
Objective: The immobility common to patients after acute stroke has the potential to increase negative mood symptoms. We evaluated the effect of very early mobilization after stroke on levels of depression, anxiety and irritability.Design: AVERT is a randomized controlled trial; patients in the very early mobilization group receive mobilization earlier (within 24 h of stroke) and more frequently than patients in the standard care group.Patients: Seventy-one patients with confirmed stroke were included.Methods: Patients were assessed on the Irritability, Depression and Anxiety (IDA) scale at multiple time-points.Results: At 7 days, very early mobilization patients were less depressed (z=2.51, p=0.012) and marginally less anxious (z=1.79, p=0.073) than standard care patients (Mann-Whitney test). Classifying IDA scores as normal or depressed, and using backward stepwise multivariable logistic regression, very early mobilization was associated with a reduced likelihood of depression at 7 days (odds ratio 0.14, 95%, confidence interval 0.03-0.61; p=0.009).Conclusion: Very early mobilization may reduce depressive symptoms in stroke patients at 7 days post-stroke.