Characterization and comparison of local onset and remote propagated electrographic seizures recorded with intracranial electrodes
Characterization and comparison of local onset and remote propagated electrographic seizures recorded with intracranial electrodes
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DOI：
10.1111/j.1528-1157.1998.tb01390.x
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发表时间：
1998-04-01
期刊：
影响因子：
5.6
通讯作者：
Sharbrough, FW
中科院分区：
文献类型：
--
作者：
Schiller, Y;Cascino, GD;Sharbrough, FW
目的：比较慢性脑电地形图记录的局灶性和远传播性发作的发作放电模式。方法：对88例连续接受慢性脑电监测的患者的电生理资料进行回顾性分析。通过盲法目测和计算机分析，确定局部和远处发作点的早期和晚期放电模式。结果：局部发作点出现4种早期和3种晚期发作模式。早期的四种模式包括β范围的节律性放电(“β嗡嗡”)、节律性的α-theta活动、三角洲范围的节律性尖锐波和不规则的尖峰放电。三种不同的延迟放电模式包括晚期的β嗡嗡声，节律性的尖锐的theta活动，以及节律性的多峰和波的放电。在远距离传播部位，记录它们的早期放电模式。第一种是远程传播的脑电惊厥所特有的，由节律性的theta-Delta活动组成，该活动与局部发作部位的并发活动相关。结论：用颅内电极记录的发作期放电模式有助于区分局部发作性和远程传播性发作，节律性的Tha-Delta活动是远处传播性部位所特有的。然而，一类远程传播的电描记子发作的初始放电由一种独立的模式组成，与在局部起病部位观察到的模式没有区别。
Purpose: To compared the ictal discharge patterns between local onset and remote propagated electrographic seizures recorded with chronic intracranial electrodes.Methods: The electrophysiological data from 88 consecutive patients who underwent chronic intracranial EEG monitoring were retrospectively reviewed. The early and late discharge patterns of electrographic seizures at local onset and distant propagated sites were determined by blinded visual inspection and computerized analysis.Results: Four early and three late electrographic seizure patterns were observed at the local onset sites. The four early patterns consisted of a rhythmic discharge in the beta range ("beta buzz"), rhythmic alpha-theta activity, rhythmic sharp waves in the delta range, and an irregular spike discharge. The three distinct late-discharge patterns consisted of a late beta buzz, rhythmic sharp theta activity, and a rhythmic polyspike and wave discharge. At remote propagated sites, electrographic their early discharge pattern. The first was unique to remote propagated electrographic seizures and consisted of a rhythmic theta-delta activity correlated with the concurrent activity at the local-onset site. The second remote initiation type consisted of patterns indistinguishable from the earlier discharge patterns recorded at the local onset site.Conclusions: The initial ictal discharge pattern recorded with intracranial electrodes can assist in differentiating local onset and remote propagated electrographic seizures, with rhythmic round theta-delta activity being unique to distant propagated sites. Nevertheless, the initial discharge of a subclass of remote propagated electrographic seizures consists of an independent pattern indistinguishable from that observed at local onset sites.