Adaptation of Marrow Sinus Wall to Fluctuation in the Rate of Cell Delivery: Studies in Rabbits after Blood‐letting
Adaptation of Marrow Sinus Wall to Fluctuation in the Rate of Cell Delivery: Studies in Rabbits after Blood‐letting
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骨髓窦壁对细胞输送速率波动的适应：放血后兔子的研究
DOI：
10.1111/j.1365-2141.1977.tb00559.x
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发表时间：
1977
影响因子：
6.5
通讯作者：
M. Tavassoli
中科院分区：
文献类型：
--
作者：
M. Tavassoli
取计算血量的25%前后，测定骨髓窦壁上皮细胞覆盖程度。外膜细胞覆盖区域的显著减少与早期网织细胞对放血的反应一致。在对照动物中，偶尔在胞质过程中观察到分散的微丝。在静脉切开后，这些细丝更频繁地被观察到，并以带状结构出现，这提高了对细胞流量波动的响应中，周周外内膜细胞发挥积极作用的可能性。
The extent of marrow sinus wall coverage by perisinal adventitial cells was measured before and after removing 25% of the calculated blood volume in rabbits. A marked reduction in the area covered by adventitial cells was recorded coinciding with the early reticulocyte response to phlebotomy. In control animals, only scattered microfilaments were occasionally observed in the cytoplasmic process of adventitial cells. After phlebotomy, these filaments were more frequently observed and appeared as band‐like structures, raising the possibility of an active role for perisinal adventitial cells in response to fluctuations in the magnitude of cell traffic.