Chemistry of iron oxophlorins. 2. Oxidation of the iron(III) octaethyloxophlorin dimer and observation of stepwise, two-electron oxidation of the oxophlorin macrocycle
Chemistry of iron oxophlorins. 2. Oxidation of the iron(III) octaethyloxophlorin dimer and observation of stepwise, two-electron oxidation of the oxophlorin macrocycle
复制标题
氧代铁蛋白的化学。
DOI：
10.1021/ja00078a024
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发表时间：
1993
影响因子：
15
通讯作者：
Edward P. Zovinka
中科院分区：
文献类型：
--
作者：
A. Balch;L. Latos‐Grażyński;B. Noll;L. Szterenberg;Edward P. Zovinka
氧化的铁oxophlorin（meso-羟基卟啉）配合物已被研究，以了解基本的化学反应，这可能有助于血红素的破坏，是由血红素加氧酶催化。八乙基氧代卟啉铁（III）二聚体[Fe III（OEPO）] 2与分子溴反应，形成两种新的高度氧化的络合物，BrFe III（OEPO）。）和Br 2 Fe III（OEPOx）（其中OEPO . OEPOx和OEPOx分别是八乙基氧代菲林二价阴离子自由基和氧化的八乙基氧代菲林一价阴离子），其中实验数据表明，是配体而不是铁发生了氧化
The oxidation of iron oxophlorin (meso-hydroxyporphyrin) complexes has been studied in order to understand the basic chemical reactivity which may contribute to the heme destruction that is catalyzed by heme oxygenase. Reaction of the iron(III) octaethyloxopblorin dimer [Fe III (OEPO)] 2 with molecular bromine results in the formation of two new, highly oxidized complexes, BrFe III (OEPO . ) and Br 2 Fe III (OEPOx) (where OEPO . and OEPOx are the octaethyloxophlorin dianion radical and the oxidized octaethyloxophlorin monoanion, respectively), in which the experimental data suggest that it is the ligand rather than the iron that has undergone oxidation