DPPH radical scavenging reaction of hydroxy- and methoxychalcones
DPPH radical scavenging reaction of hydroxy- and methoxychalcones
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DOI：
10.1271/bbb.70.193
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发表时间：
2006-01-01
影响因子：
1.6
通讯作者：
Kawabata, J
中科院分区：
文献类型：
--
作者：
Nishida, J;Kawabata, J
在醇和非醇溶剂中评价了带有2，3-和3，4-二羟基化和3，4，5-三羟基化B-环的2 ′，4，6 ′-三羟基-和2 ′-羟基-4 ′，6 ′-二甲氧基查耳酮的DPPH自由基清除活性。所有的测试化合物清除超过两个当量的自由基通过可能的转化为相应的B-环醌，并在大多数情况下，随后进行环化的anrones和黄烷酮，这些被确定在反应溶液中通过原位NMR分析。有趣的是，2 '，3，4-三羟基-4，6-二甲氧基查耳酮和DPPH自由基之间的反应受到所用溶剂的显著影响，这可能是由于环化成橙酮的准备程度不同。
The DPPH radical scavenging activity of 2',4,6'-trihydroxy- and 2'-hydroxy-4',6'-dimethoxychalcones carrying a 2,3- and 3,4-dihydroxylated, and 3,4,5-trihydroxylated B-ring was evaluated in alcoholic and non-alcoholic solvents. All test compounds scavenged more than two equivalent of radicals by a possible conversion to the corresponding B-ring quinones and in most cases subsequently underwent cyclization to anrones and flavanones, these being identified in the reaction solutions by an in situ NMR analysis. Interestingly, the reaction between 2',3,4-trihydroxy-4,6-dimethoxychalcone and the DPPH radical was significantly affected by the solvent used, which might be accounted for by the difference in readiness for cyclization to an aurone.