Impact of COVID-19 related policy changes on filling of opioid and benzodiazepine medications.

Impact of COVID-19 related policy changes on filling of opioid and benzodiazepine medications.
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COVID-19 相关政策变化对阿片类药物和苯二氮卓类药物灌装的影响。

DOI:
10.1016/j.sapharm.2020.06.003
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发表时间:
2021-01
期刊:
Research in social & administrative pharmacy : RSAP
影响因子:
--
通讯作者:
Thornton JD
Thornton JD
中科院分区:
其他
文献类型:
--
作者:
Downs CG;Varisco TJ;Bapat SS;Shen C;Thornton JD

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在COVID-19疫情期间,医疗服务的可及性发生了巨大变化。选择性医疗程序,包括例行门诊,受到限制,引起了对阿片类药物和苯二氮卓类药物提供者和处方可用性的担忧。研究因COVID-19取消择期医疗程序如何影响德克萨斯州阿片类药物和苯二氮卓类药物处方的分配。中断时间序列分析进行检查阿片类药物和苯二氮卓类药物的处方趋势的变化之前和之后的选择性医疗程序的限制。从德克萨斯州处方监测计划中确定了2020年1月5日至2020年5月12日期间服用阿片类药物或苯二氮卓类药物处方的患者样本。择期医疗程序从2020年3月23日开始受到限制,表明干预期开始。限制择期手术分别与填写和开具阿片类药物处方的患者数量(β = −6029,95%CI = −8810.40,−3246.72)和处方者数量(β = −2784,95%CI = −3671.09,−1896.19)显著减少相关。此外,服用苯二氮卓类药物处方的患者数量显著减少(β = −1982,95%CI = −3712.43,−252.14),处方者数量也显著减少(β = −708.62,95%CI = −1190.54,−226.71)。限制择期手术导致服用阿片类药物或苯二氮卓类药物处方的患者存在较大的护理缺口。
Healthcare access has changed drastically during the COVID-19 pandemic. Elective medical procedures, including routine office visits, were restricted raising concerns regarding opioid and benzodiazepine provider and prescription availability. To examine how the cancelation of elective medical procedures due to COVID-19 impacted the dispensing of opioid and benzodiazepine prescriptions in Texas. Interrupted time series analyses were preformed to examine changes in prescription trends for opioids and benzodiazepines before and after the restriction on elective medical procedures. Samples of patients who filled an opioid or benzodiazepine prescription from January 5, 2020 to May 12, 2020 were identified from the Texas Prescription Monitoring Program. Elective medical procedures were restricted starting March 23, 2020 indicating the beginning of the intervention period. Restricting elective procedures was associated with a significant decrease in the number of patients (β = −6029, 95%CI = −8810.40, −3246.72) and prescribers (β = −2784, 95%CI = −3671.09, −1896.19) filling and writing opioid prescriptions, respectively. Also, the number of patients filling benzodiazepine prescriptions decreased significantly (β = −1982, 95%CI = −3712.43, −252.14) as did the number of prescribers (β = −708.62, 95%CI = −1190.54, −226.71). Restricting elective procedures resulted in a large care gap for patients taking opioid or benzodiazepine prescriptions.
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