SINGLE-CHANNEL CURRENTS ACTIVATED BY LIGHT IN LIMULUS VENTRAL PHOTORECEPTORS
SINGLE-CHANNEL CURRENTS ACTIVATED BY LIGHT IN LIMULUS VENTRAL PHOTORECEPTORS
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DOI：
10.1038/304268a0
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发表时间：
1983-01-01
期刊：
影响因子：
64.8
通讯作者：
LISMAN, JE
中科院分区：
文献类型：
--
作者：
BACIGALUPO, J;LISMAN, JE
感觉刺激改变了受体细胞的膜电导。对几种类型的受体1-4的噪声分析研究表明，离子通道介导了电导的这种变化，但没有获得这种通道的直接证据。我们现在已经用膜片钳技术研究了光诱导电导背后的离子渗透机制，并解决了光激活的单通道电流。
Sensory stimuli alter the membrane conductance of receptor cells. Noise analysis studies in several types of receptors1–4suggest that ionic channels mediate this change in conductance, but no direct evidence for such channels has been obtained. We have now investigated the mechanism of ion permeation underlying the light-induced conductance in the ventral photoreceptors ofLimulus polyphemusby means of the patch-clamp technique5and have resolved single-channel currents that are activated by light.