Agreement Between 10-2 and 24-2C Visual Field Test Protocols for Detecting Glaucomatous Central Visual Field Defects.
Agreement Between 10-2 and 24-2C Visual Field Test Protocols for Detecting Glaucomatous Central Visual Field Defects.
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DOI：
10.1097/ijg.0000000000001844
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发表时间：
2021-06-01
影响因子：
2
通讯作者：
Zangwill LM
中科院分区：
文献类型：
--
作者：
Chakravarti T;Moghadam M;Proudfoot JA;Weinreb RN;Bowd C;Zangwill LM
评估 Humphrey 视野分析仪 10-2 和 24-2C 测试协议之间的一致性，用于检测中央 10° 视野 (CVFD) 的青光眼缺陷。包括 18 名健康个体、12 名青光眼疑似者和 62 名青光眼患者的 165 只眼睛的 VF，他们在六个月内完成了 10-2 和 24-2C VF 测试方案。 10-2 和 24-2C（中心 22 个点内）测试网格上的 CVFD 需要 TD 或 PD 图上半场内 p<5%、5% 和 1% 或 <5%、2% 和 2% 的 3 个连续点的簇。 Cohen 的 Kappa (k) 用于评估 10-2 和 24-2C 测试网格在识别 CVFD 方面的一致性。每种测试策略的特异性均通过健康眼睛的 VF 进行评估。根据 10-2 和 24-2C 测试网格的 TD 和 PD 图，将可疑眼和青光眼眼中的 CVFD 合并并报告为定位于上半视野、下半视野或两个半视野。在从 PD (k=0.551) 和 TD (k=0.651) 图检测任何 CVFD 时，在 10-2 和 24-2C 网格之间观察到中等至显着的一致性。两种测试方案在健康眼睛中的特异性都很高，范围为 0.94 至 1.0。使用 24-2C 和 10-2 协议识别 CVFD 的实质性一致表明，通过在 24-2 测试网格中添加中心测试点来组合测试可能会取代两种视野检查方案来检测中央和周边青光眼视野损伤的需要。用于检测中心视野缺陷的 10-2 和 24-2C 视野检查之间的中度至实质性一致性表明，在 24-2 方案中添加中心测试点可以提高青光眼管理视野测试的效率。
To assess agreement between Humphrey Visual Field Analyzer 10-2 and 24-2C test protocols for detecting glaucomatous defects in the central 10° of the visual field (CVFDs). VFs from 165 eyes of 18 healthy individuals, 12 glaucoma suspects and 62 glaucoma patients who completed 10-2 and 24-2C VF testing protocols within six months were included. CVFDs on 10-2 and 24-2C (within the central 22 points) test grids required a cluster of 3 contiguous points with p<5%, 5% and 1% or <5%, 2%, and 2% within a hemifield on the TD or PD plot. Cohen’s Kappa (k) was used to assess agreement between 10-2 and 24-2C test grids in identifying CVFDs. Specificity of each testing strategy was assessed in VFs from healthy eyes. CVFDs in suspect and glaucoma eyes were combined and reported as localized to superior, inferior or both hemifields based on TD and PD plots for 10-2 and 24-2C test grids. Moderate to substantial agreement was observed between 10-2 and 24-2C grids for detecting any CVFD from PD (k=0.551) and TD (k=0.651) plots. Specificity was high in healthy eyes ranging from 0.94 to 1.0 for both test protocols. Substantial agreement for identifying CVFDs using the 24-2C and 10-2 protocols suggests that combining tests by adding central test points to the 24-2 test grid may supplant the need for two perimetry regimens for detecting central and peripheral glaucomatous visual field damage. Moderate to substantial agreement between 10-2 and 24-2C perimetry for detecting central field defects suggests that adding central test points to the 24-2 protocol may improve efficiency of visual field testing for glaucoma management.