Spirometric reference equations for Algerians aged 19 to 73 years
Spirometric reference equations for Algerians aged 19 to 73 years
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DOI：
10.1016/s0761-8425(08)71615-2
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发表时间：
2008-05-01
影响因子：
0.6
通讯作者：
Mehdioui, H.
中科院分区：
文献类型：
--
作者：
Bougrida, M.;Ben Saad, H.;Mehdioui, H.
引言尚未评估使用欧洲参考方程解释阿尔及利亚患者肺量测定结果的有效性。目的：（i）建立阿尔及利亚肺量计参考方程和（ii）与欧洲的比较。记录性别、年龄、身高、体重、瘦体重（LM）、脂肪量百分比（%FM）和体重指数（BMI）。根据国际指南，使用身体体积描记器测量肺活量变量。进行简单和多重线性回归。测定用力呼气量（FEV 1）、用力肺活量（FVC）及FEV 1/慢肺活量比值结果273例健康人的FEV 1/SVC与欧洲参考方程预测值比较（120名女性）（年龄：42 +/- 14岁;身高：1.69 +/- 0.10 m;体重：74 +/- 13 kg; LM：59 +/- 10 kg; %FM：21 +/- 6%; BMI：26 +/- 6 Kg.m（-2））。(i)阿尔及利亚参考方程解释了17%至68%的变异性参数测试。(ii)欧洲肺功能参考方程明显低估了FEV 1、FVC和FEV 1/SVC比值（分别为0.38 ± 0.45L、0.36 ± 0.55L和0.01 ± 0.06）。
Introduction The validity of using European reference equations in the interpretation of spirometry results in Algerian patients has not been assessed. Aims: (i) to establish Algerian spirometric reference equations and (ii) to compare them with European ones.Methods A medical questionnaire was administered. Gender, age, height, weight, lean mass (LM), percentage of fat mass (%FM) and body mass index (BMI) were noted. Spirometric variables were measured using a body plethysmograph according to international guidelines. Simple and multiples linear regressions were performed. The measured forced expiratory volume (FEV1), forced vital capacity (FVC) and the ratio between FEV1 and slow vital capacity (FEV1/SVC) were compared with those predicted from European reference equations.Results 273 healthy subjects (120 women) were included (age: 42 +/- 14 years; height: 1.69 +/- 0.10 m; weight: 74 +/- 13 kg; LM: 59 +/- 10 kg; %FM: 21 +/- 6%; BMI: 26 +/- 6 Kg.m(-2)). (i) Algerian reference equations explained 17% to 68% of the variability of parameters tested. (ii) The European reference equations significantly underestimated the measured FEV1, FVC and the FEV1/SVC ratio (respectively, 0.38 +/- 0.45 L, 0.36 +/- 0.55 L, and 0.01 +/- 0.06).Conclusion The use of Algerian spirometric reference equations should improve the accuracy of lung function interpretation in this population.