Multiweek Experiments for an Inorganic Chemistry Laboratory Course: Synthesis of Nickel Complexes Supported by a Tetradentate Ligand with a N 2 O 2 Donor Set
Multiweek Experiments for an Inorganic Chemistry Laboratory Course: Synthesis of Nickel Complexes Supported by a Tetradentate Ligand with a N 2 O 2 Donor Set
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无机化学实验室课程的多周实验：由具有 N 2 O 2 供体组的四齿配体支持的镍配合物的合成
DOI：
10.1021/acs.jchemed.0c01117
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发表时间：
2021
影响因子：
3
通讯作者：
Guan, Hairong
中科院分区：
文献类型：
--
作者：
Collett, Joel D.;Krause, Jeanette A.;Guan, Hairong
无机化学教授学生这样的概念：配体结构的修饰，尤其是供体性质，可以对金属配合物的反应性和稳定性产生巨大影响。这里描述的实验通过研究衍生自邻苯二胺和水杨醛的两种四齿配体强化了这一概念。席夫碱配体 H2salophen 与 Ni(OAc)2·4H2O 反应生成栗色、方形平面络合物 Ni(salophen)。在相同条件下，胺型配体 H2salophan 形成浅蓝色化合物，分析为 [Ni(Hsalophan)(OAc)]2。不含乙酸盐的Ni(salophan)络合物可由H2salophan与Ni(OAc)2·4H2O在NaOH存在下反应产生，但经过配体脱氢生成Ni(salophen)。进行这些实验的学生有机会学习合成技术和各种表征方法。最重要的是，以探究为导向的实验设计可以帮助他们培养批判性思维能力，并应用所获得的知识来解决实验室课程中的研究问题。
Inorganic Chemistry teaches students the concept that modifications to ligand structures, especially the donor properties, can have a drastic impact on the reactivity and stability of the metal complexes. Experiments described here reinforce this concept through the investigation of two tetradentate ligands derived fromo-phenylenediamine and salicylaldehyde. The Schiff base ligand, H2salophen, reacts with Ni(OAc)2·4H2O to yield a maroon, square planar complex, Ni(salophen). Under the same conditions, the amine-type ligand, H2salophan, forms a light-blue compound analyzed as [Ni(Hsalophan)(OAc)]2. The Ni(salophan) complex free of acetate may be produced from the reaction of H2salophan with Ni(OAc)2·4H2O in the presence of NaOH but undergoes ligand dehydrogenation to yield Ni(salophen). Students conducting these experiments have the opportunity to learn synthetic techniques and various characterization methods. Most importantly, the inquiry-guided experimental design helps them develop critical thinking skills and apply acquired knowledge to solving a research problem in a laboratory course.