Automated analysis of the auditory brainstem response using derivative estimation wavelets
Automated analysis of the auditory brainstem response using derivative estimation wavelets
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DOI：
10.1159/000081544
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发表时间：
2005-01-01
影响因子：
1.6
通讯作者：
Wilson, WJ
中科院分区：
文献类型：
--
作者：
Bradley, AP;Wilson, WJ
在本文中，我们描述了一种自动检测和标记正常阈上听觉脑干反应（ABR）的峰值 I - VII 的算法。该算法分三个阶段进行，可选择第四个阶段：(1) 使用一阶导数的过零来识别 ABR 波形中的所有候选峰和谷，(2) 根据这些候选峰的潜伏期和形态来识别峰 I - VII，(3) 如果需要，使用二阶导数的过零将峰 II 和 IV 识别为拐点，(4) 在峰值潜伏期和振幅确定之前识别峰间谷。测量。该算法的性能是根据使用 90 dBnHL 刺激强度记录的一组 240 个正常 ABR 波形进行评估的。与专业听力学家相比，该算法正确识别了 96 - 98% 波形中的主要 ABR 峰值（I、III 和 V）以及 45 - 83% 波形中的次要 ABR 峰值（II、IV、VI 和 VII）。虽然只有 83% 的波形正确识别了峰 II，77% 的波形正确识别了峰 IV，但结果表明，5% 的峰 II 识别和 31% 的峰 IV 识别是允许将这些峰发现为拐点的直接结果。版权所有 (C) 2005 S. Karger AG，巴塞尔。
In this paper, we describe an algorithm that automatically detects and labels peaks I - VII of the normal, suprathreshold auditory brainstem response (ABR). The algorithm proceeds in three stages, with the option of a fourth: ( 1) all candidate peaks and troughs in the ABR waveform are identified using zero crossings of the first derivative, ( 2) peaks I - VII are identified from these candidate peaks based on their latency and morphology, ( 3) if required, peaks II and IV are identified as points of inflection using zero crossings of the second derivative and ( 4) interpeak troughs are identified before peak latencies and amplitudes are measured. The performance of the algorithm was estimated on a set of 240 normal ABR waveforms recorded using a stimulus intensity of 90 dBnHL. When compared to an expert audiologist, the algorithm correctly identified the major ABR peaks ( I, III and V) in 96 - 98% of the waveforms and the minor ABR peaks ( II, IV, VI and VII) in 45 - 83% of waveforms. Whilst peak II was correctly identified in only 83% and peak IV in 77% of waveforms, it was shown that 5% of the peak II identifications and 31% of the peak IV identifications came as a direct result of allowing these peaks to be found as points of inflection. Copyright (C) 2005 S. Karger AG, Basel.