Strain rate imaging for noninvasive functional quantification of the left atrium: Comparative studies in controls and patients with atrial fibrillation
Strain rate imaging for noninvasive functional quantification of the left atrium: Comparative studies in controls and patients with atrial fibrillation
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DOI：
10.1016/j.echo.2004.12.005
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发表时间：
2005-07-01
影响因子：
6.5
通讯作者：
Shimamoto, K
中科院分区：
文献类型：
--
作者：
Inaba, Y;Yuda, S;Shimamoto, K
应变率 (SR) 成像能够定量测量左心室 (IV) 功能，而与心脏平移无关。然而，SR 成像是否适用于检测左心房 (LA) 功能障碍仍不清楚。本研究的目的是评估通过 SR 成像测量 LA 功能的可行性，重点关注房颤 (AF) 期间衰老和 LA 扩张的影响。对 50 名对照者（29 名男性和 21 名女性；平均年龄，41 +/- 14 岁）和 27 名 AF 患者（15 名男性和 12 名女性；平均年龄，62 +/- 12 岁；8 例持续性 AF 和 19 例阵发性 AF）进行超声心动图评估，从 3 个心尖视图进行分析并进行离线分析。测量每个 LA 节段（隔膜、外侧、后、前和下）的峰值 SR，并通过对每个节段的结果进行平均来计算平均峰值收缩期 SR (SR-LAs)、舒张早期 SR (SR-LAe) 和舒张晚期 SR (SR-LAa)。 LA 尺寸、舒张末期峰值二尖瓣和肺动脉速度、LA 缩短分数和心房充盈分数被计算为 LA 功能参数。平均 SR-LAs、SR-LAe 和 SR-LAa 的正常值分别为 3.4 +/- 1.0 s(-1)、-3.9 +/- 1.7 s(-1) 和 -3.1 +/- 1.0 s(-1)，并且在超过 95% 的 LA 节段中成功测量。在对照组中，平均 SR-LAs 和平均 SR-LAe 均与年龄、LA 尺寸以及舒张早期和晚期二尖瓣血流速度比相关。相反，平均 SR-LAa 与年龄或 LA 功能参数没有显着相关性。在 AF 患者中，平均 SR-LA 与年龄成反比。持续性房颤患者的平均 SR-LA 显着低于年龄匹配的对照组（1.7 +/- 0.8 vs 2.9 +/- 0.9 s(-1)；P
Strain rate (SR) imaging enables quantitative measurement of left ventricular (IV) function independent of cardiac translation. However, whether SR imaging is applicable for detection of left atrial (LA) dysfunction remains unknown. The purpose of this study was to assess the feasibility of measuring LA function by SR imaging, focusing on the effects of aging and LA dilatation during atrial fibrillation (AF). Echocardiographic evaluation including SR imaging was performed in 50 controls (29 males and 21 females; mean age, 41 +/- 14 years) and in 27 patients with AF (15 males and 12 females; mean age, 62 +/- 12 years; 8 with persistent AF and 19 with paroxysmal AF) from 3 apical views and analyzed off-line. Peak SR was measured at each LA segment (septum, lateral, posterior, anterior, and inferior), and mean peak systolic SR (SR-LAs), early diastolic SR (SR-LAe), and late diastolic SR (SR-LAa) were calculated by averaging the results for each segment. LA dimension, peak mitral and pulmonary velocities at late diastole, LA fractional shortening, and atrial filling fraction were calculated as parameters of LA function. Normal values for mean SR-LAs, SR-LAe, and SR-LAa were 3.4 +/- 1.0 s(-1), -3.9 +/- 1.7 s(-1), and -3.1 +/- 1.0 s(-1), respectively, and they were successfully measured in more than 95% of the LA segments. In controls, both mean SR-LAs and mean SR-LAe correlated with age, LA dimension, and early to, late diastolic mitral flow velocity ratio. Conversely, mean SR-LAa did not show significant correlation with age or parameters of LA function. In AF patients, mean SR-LAs was correlated inversely with age. The mean SR-LAs was significantly lower in persistent AF patients than in age-matched controls (1.7 +/- 0.8 vs 2.9 +/- 0.9 s(-1); P