Bioprospecting potential of the soil metagenome: novel enzymes and bioactivities.
Bioprospecting potential of the soil metagenome: novel enzymes and bioactivities.
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DOI：
10.5808/gi.2013.11.3.114
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发表时间：
2013-09
影响因子：
--
通讯作者：
Lee SW
中科院分区：
文献类型：
--
作者：
Lee MH;Lee SW
土壤生态系统中的微生物多样性高于任何其他微生物生态系统。大多数土壤微生物尚未被鉴定，因为优势成员在标准培养基上不易培养;因此，土壤生态系统是发现新型微生物酶和生物活性的巨大水库。土壤宏基因组是微生物基因组的集合体，可以直接从土壤中克隆和测序，以寻找新的微生物资源。本文综述了土壤中微生物多样性的研究进展以及从土壤宏基因组中寻找微生物资源的研究进展，重点介绍了宏基因组学在土壤微生物资源勘探中的应用前景和最新发现。
The microbial diversity in soil ecosystems is higher than in any other microbial ecosystem. The majority of soil microorganisms has not been characterized, because the dominant members have not been readily culturable on standard cultivation media; therefore, the soil ecosystem is a great reservoir for the discovery of novel microbial enzymes and bioactivities. The soil metagenome, the collective microbial genome, could be cloned and sequenced directly from soils to search for novel microbial resources. This review summarizes the microbial diversity in soils and the efforts to search for microbial resources from the soil metagenome, with more emphasis on the potential of bioprospecting metagenomics and recent discoveries.