Detection of unusual lipid mixing in cholesterol-rich phospholipid bilayers: the long and the short of it.
Detection of unusual lipid mixing in cholesterol-rich phospholipid bilayers: the long and the short of it.
复制标题
检测富含胆固醇的磷脂双层中的异常脂质混合：其长和短。
DOI：
10.1021/ja0359355
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发表时间：
2003
影响因子：
15
通讯作者：
Regen,StevenL
中科院分区：
文献类型：
--
作者：
Tokutake,Nobuya;Jing,Bingwen;Regen,StevenL
最近邻识别研究表明，当甾醇含量足够高时，在含有相对长(高熔点)和短(低熔点)磷脂的流体双层中，受青睐的甾醇−磷脂结合可以逆转；也就是说，类脂现在成为受青睐的近邻。简要讨论了这种效应的可能来源。
Nearest-neighbor recognition studies have revealed that favored sterol−phospholipid associations can be reversed in a fluid bilayer that contains relatively long (high melting) and short (low melting) phospholipids, when the sterol content is sufficiently high; that is, like-lipids now become favored nearest-neighbors. A possible origin of this effect is briefly discussed.