Bacterial biofilms in the human gastrointestinal tract.
Bacterial biofilms in the human gastrointestinal tract.
复制标题
人类胃肠道中的细菌生物膜。
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
G. Gibson
中科院分区：
文献类型：
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作者：
H. Probert;G. Gibson
1936年首次描述了微生物生物膜，随后的研究揭示了它们的普遍性和与自由生活（浮游）微生物的生理差异。鉴于其新兴的意义，本文综述了人体胃肠道内的细菌生物膜。注意这些粘膜相关群体的性质，关注由宿主上皮细胞持续分泌粘液提供的受保护的环境。它还检查了各种细菌物种所具有的属性，这些属性有助于这种微环境的栖息。此外，对比之间的寄生菌的内腔和固着（生物膜）细菌生长密切相关的宿主细胞和食物颗粒。特别是这两个馏分所表现出的不同的发酵概况进行了讨论。这些社区在宿主健康和疾病中的潜在作用，以及内腔人口的稳定，也被考虑。提到了这些鲜为人知的人群和宿主上皮细胞之间存在的互惠共生状态，从而突出了它们在胃肠道健康方面的生态意义。
Microbial biofilms were first described in 1936 and subsequent research has unveiled their ubiquity and physiological distinction from free-living (planktonic) microorganisms. In light of their emerging significance this review examines the bacterial biofilms within the human gastrointestinal tract. Attention is paid to the nature of these mucosally- associated populations, focusing on the protected environment afforded by the continual secretion of mucus by host epithelial cells. It also examines the attributes possessed by various bacterial species that facilitate habitation of this microenvironment. Additionally, contrasts are drawn between planktonic bacteria of the lumen and sessile (biofilm) bacteria growing in close association with host cells and food particles. In particular the different fermentation profiles exhibited by these two fractions are discussed. The potential role of these communities in host health and disease, as well as the stabilisation of the lumenal population, is also considered. Reference is made to the state of mutualism that exists between these little understood populations and the host epithelia, thus highlighting their ecological significance in terms of gastrointestinal health.
螺旋体周质鞭毛和运动性。
DOI：
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发表时间：
2000
期刊：
Journal of molecular microbiology and biotechnology.
影响因子：
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作者：
Li,C;Motaleb,A;Sal,M;Goldstein,SF;Charon,NW
通讯作者：
Charon,NW