Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report
Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report
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DOI：
10.1080/23744235.2020.1747634
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发表时间：
2020-03-30
影响因子：
5.8
通讯作者：
Eftekhari, Kambiz
中科院分区：
文献类型：
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作者：
Aghdam, Mojtaba Kamali;Jafari, Nahid;Eftekhari, Kambiz
新型冠状病毒或冠状病毒病（COVID-19）可影响所有年龄组。儿童和婴儿的临床病程较成人轻。应该指出的是，虽然儿童可能出现典型症状，但新生儿可能出现非特异性症状。这种疾病在新生儿中很少见，因此，对这一群体的怀疑有助于快速诊断。病例报告：一名15天大的新生儿因发热、嗜睡、皮肤斑纹和呼吸窘迫入院，无咳嗽。他的母亲有新型冠状病毒的症状。因此，对新生儿进行了逆转录聚合酶链反应（RT-PCR）检测，结果呈阳性。新生儿被隔离并接受支持性护理。开始抗生素和抗病毒治疗。最后，婴儿出院时总体情况良好。结论：当新生儿出现非特异性感染症状且其父母有新增COVID-19病史时，提示需要进行新型冠状病毒PCR检测。
Introduction: Novel coronavirus or coronavirus disease (COVID-19) can affect all age groups. The clinical course of the disease in children and infants is milder than in adults. It should be noted that, although typical symptoms may be present in children, non-specific symptoms could be noted in the neonate. The disease is rare in the neonate, so, its suspicion in this group can help to make a quick diagnose. Case report: A 15-day-old neonate was admitted with fever, lethargy, cutaneous mottling, and respiratory distress without cough. His mother had symptoms of Novel coronavirus. So Reverse-Transcription Polymerase Chain Reaction (RT-PCR) assay was done for the neonate and showed to be positive. The newborn was isolated and subjected to supportive care. Antibiotic and antiviral treatment was initiated. Eventually, the baby was discharged in good general condition. Conclusion: When a newborn presents with non-specific symptoms of infection with an added history of COVID-19 in his/her parents, it indicates the need for PCR testing for Novel coronavirus.