Pathophysiology of migraine chronification
Pathophysiology of migraine chronification
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DOI：
10.1007/s10072-010-0264-y
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发表时间：
2010-06-01
影响因子：
3.3
通讯作者：
Saracco, M. G.
中科院分区：
文献类型：
--
作者：
Aguggia, M.;Saracco, M. G.
偏头痛是一种常见的致残、未诊断和未得到充分治疗的神经科疾病。它是一种慢性、复发性疾病，具有间歇性表现，在一些有临床、生理和解剖学基础的个体中呈进行性发展。进展可能是由于产生偏头痛发作的机制或由发作产生的激活。慢化的潜在可补救风险因素包括偏头痛发作的频率、肥胖、过度使用药物、咖啡因过度使用、应激性生活事件、抑郁症、睡眠障碍和皮肤过敏。
Migraine is a prevalent, disabling, undiagnosed and undertreated disease in neurological practice. It is a chronic, recurrent disorder with episodic manifestations that are progressive in some individuals with clinical, physiological and anatomical bases. Progression may be due to mechanisms generating the migraine attacks or to the activation generated by the attacks. Potentially remediable risk factors for chronification include frequency of migraine attacks, obesity, excessive use of medications, caffeine overuse, stressful life events, depression, sleep disorders and cutaneous allodynia.