Quality of life of patients with scabies
Quality of life of patients with scabies
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DOI：
10.1111/j.1468-3083.2010.03618.x
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发表时间：
2010-10-01
影响因子：
9.2
通讯作者：
Xiao-peng, W.
中科院分区：
文献类型：
--
作者：
Jin-gang, A.;Sheng-xiang, X.;Xiao-peng, W.
研究背景疥疮是由疥螨引起的一种高度传染性疾病，该病在许多资源贫乏地区仍然是一个主要的公共卫生问题。除了皮肤损伤或大量发病之外，疥疮还会导致社会耻辱。然而，尚未对疥疮患者的生活质量（QoL）进行调查。目的本研究旨在利用皮肤科生活质量指数（DLQI）问卷评估疥疮对患者生活质量的影响，并评估其可行性和内部一致性。方法自8月8日起，对西安交通大学第二医院皮肤科连续100名就诊的疥疮患者进行前瞻性研究。 2008年至2008年12月20日，选择硫磺（10%）治疗疥疮。结果共有96名患者完成了研究。其中，78名（81.25%）患者在研究结束时被认为治愈。我们研究中的平均 +/- SD DLQI 评分为 10.09 +/- 5.96。我们大多数（71.9%）患者的生活质量受到中度影响。问题1（症状）、2（尴尬）、7（工作或学习）和9（性困难）对疥疮患者影响最大。领域 1（症状和感受）和领域 5（人际关系）得分高于其他领域。我们的患者在治疗后生活质量有了显着的进步。未发现疾病相关特征与生活质量之间有很强的关系。结论疥疮对患者的生活质量有一定的影响。硫可以被认为是治疗疥疮患者的有效方法。
BackgroundScabies is a highly contagious disease caused by the mite Sarcoptes scabiei, and the disease is still a major public health problem in many resource-poor regions. Apart from the skin lesions or substantial morbidity, scabies also leads to social stigma. However, quality of life (QoL) has not been investigated in patients with scabies.ObjectivesThe aim of this study was to assess the impact of scabies on patients' QoL using the Dermatology Life Quality Index (DLQI) questionnaire, and assess its feasibility and internal consistency.MethodsOne hundred consecutive outpatients seeking treatment for scabies in the Department of Dermatology, the Second Hospital of Xi'an Jiaotong University, were assessed for eligibility for this prospective study from 8 August 2008 to 20 December 2008. Sulphur (10%) was selected in the treatment of scabies.ResultsA total of 96 patients completed the study. Among them, 78 (81.25%) of patients were considered cured at the end of the study. The mean +/- SD DLQI score in our study was 10.09 +/- 5.96. QoL of most of (71.9%) our patients has moderately affected. Questions 1 (symptoms), 2 (embarrassment), 7 (work or study) and 9 (sexual difficulties) had the most impact on patients with scabies. Domain 1 (symptoms and feelings) and 5 (personal relationships) scored higher than other domains. There was significant progress of QoL after treatment in our patients. No strong relationship between disease-related characteristics and QoL could be found.ConclusionScabies moderately affected the QoL of the patients. Sulphur could be considered as an effective treatment for patients with scabies.