Alkyne metathesis catalysts : Scope and future
Alkyne metathesis catalysts : Scope and future
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DOI：
10.1016/j.molcata.2006.03.054
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发表时间：
2006-07
影响因子：
--
通讯作者：
A. Mortreux;Olivier Coutelier
中科院分区：
文献类型：
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作者：
A. Mortreux;Olivier Coutelier
本文主要从催化剂的角度介绍了自早期发现以来炔复分解反应的发展。它表明，虽然定义明确的碳炔可能是有用的，这个反应，进一步的工作已经取得，旨在合成新的催化剂或催化体系，基于钼前体，相关或不与酚类助催化剂。主要目标是获得更多的官能团耐受性催化剂，用于有机合成，包括用于环中三键的进一步立体选择性氢化的RCM，以及用于芳香二炔的聚合。给出了一些可能的机制的见解，和相关的数据的末端炔的复分解，一个仍然具有挑战性的反应，其中聚合是通过形成去质子化的metallacyclobadiene，也提出和讨论。
This paper presents the evolution of alkyne metathesis since the early discoveries, essentially from the catalyst point of view. It is shown that although well defined carbynes may be useful for this reaction, further work has been made, aimed at the synthesis of new catalysts or catalytic systems, based on molybdenum precursors, associated or not with phenolic co-catalysts. The major objectives have been to obtain more functional groups tolerants catalysts, for their application in organic synthesis, including RCM for further stereoselective hydrogenation of the triple bond in the cycle, as well as for polymerization of aromatic diynes. Some insights into the possible mechanisms are given, and data relevant to the metathesis of terminal alkynes, a still challenging reaction where polymerization is occurring via the formation of deprotonated metallacyclobutadiene, are also presented and discussed.