Synthesis and characterization of hollow magnetic nanospheres modified with Au nanoparticles for bio-encapsulation
Synthesis and characterization of hollow magnetic nanospheres modified with Au nanoparticles for bio-encapsulation
复制标题
DOI：
10.1016/j.jmmm.2016.11.004
复制
发表时间：
2017-04
影响因子：
2.7
通讯作者：
Satoshi Seisno;Ken-chi Suga;T. Nakagawa;T. Yamamoto
中科院分区：
文献类型：
--
作者：
Satoshi Seisno;Ken-chi Suga;T. Nakagawa;T. Yamamoto
成功制备了Au纳米粒子修饰的磁性空心纳米球。采用放射化学法制备了Au/SiO2纳米球，并将其作为铁氧体模板。在铁氧体镀覆过程之后，Au/SiO2模板完全被磁性纳米颗粒包覆。SiO2核的溶解导致内部含有Au纳米颗粒的空心磁性纳米球的形成。磁性纳米空心球由平均直径为60 nm的Fe 3 O 4颗粒连接形成球壁，球壁内包裹着平均直径为7.2 nm的Au颗粒。Au纳米粒子固定在SiO2模板上有助于Fe离子前体和/或Fe 3 O 4种子的吸附。这些空心磁性纳米球被认为是一种新型的纳米载体，因为Au颗粒可以特异性地将生物分子固定在空心球内。
Hollow magnetic nanospheres modified with Au nanoparticles were successfully synthesized. Au/SiO2nanospheres fabricated by a radiochemical process were used as templates for ferrite templating. After the ferrite plating process, Au/SiO2templates were fully coated with magnetite nanoparticles. Dissolution of the SiO2core lead to the formation of hollow magnetic nanospheres with Au nanoparticles inside. The hollow magnetic nanospheres consisted of Fe3O4grains, with an average diameter of 60 nm, connected to form the sphere wall, inside which Au grains with an average diameter of 7.2 nm were encapsulated. The Au nanoparticles immobilized on the SiO2templates contributed to the adsorption of the Fe ion precursor and/or Fe3O4seeds. These hollow magnetic nanospheres are proposed as a new type of nanocarrier, as the Au grains could specifically immobilize biomolecules inside the hollow sphere.