Cannabis and Prescription Drug Use Among Older Adults With Functional Impairment.
Cannabis and Prescription Drug Use Among Older Adults With Functional Impairment.
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DOI：
10.1016/j.amepre.2021.01.042
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发表时间：
2021-08
影响因子：
5.5
通讯作者：
Palamar JJ
中科院分区：
文献类型：
--
作者：
Han BH;Le A;Funk-White M;Palamar JJ
使用精神活性物质对有功能障碍的成年人可能有风险。本研究调查了美国报告功能损伤的年龄≥50岁的成年人中大麻使用和处方阿片类药物和镇静剂/镇静剂（误用）的情况。根据报告的功能损伤数量，对2015-2019年全国药物使用和健康调查队列中年龄≥50岁的成年人进行横断面分析，估计了过去一年医疗和非医疗大麻使用以及处方阿片类药物和镇静剂/镇静剂使用和滥用的流行程度。使用逻辑回归估计每种物质的医疗和非医疗使用或滥用与任何损害、损害数量和特定损害相关的调整几率。分析于2020年12月进行。与无损伤的患者相比，有损伤的患者更有可能报告使用大麻和（错误）使用处方阿片类药物和镇静剂/镇静剂（均p<0.05）。随着损伤数量的增加，每种药物的误用发生率也增加（均p<0.001）。有任何损害与医用大麻使用的几率增加相关（AOR=2.28, 95% CI=1.57, 3.30），但与非医疗使用无关，与滥用处方阿片类药物（AOR=1.62, 95% CI=1.38, 1.91）和镇静剂/镇静剂（AOR=1.59, 95% CI=1.20, 2.11）的几率增加相关。思维受损与使用和滥用每种物质的几率增加有关，办事能力受损与处方阿片类药物滥用的几率增加有关（AOR=1.34, 95% CI=1.01, 1.78）。在年龄≥50岁的成年人中，处方药滥用与功能损伤有关，并可能对这一脆弱人群构成潜在风险。
Psychoactive substance use may be risky for adults with functional impairments. This study investigates cannabis use and prescription opioid and tranquilizer/sedative (mis)use among adults aged ≥50 years reporting functional impairments in the U.S. This cross-sectional analysis of adults aged ≥50 years from the 2015–2019 cohorts of the National Survey on Drug Use and Health estimates the prevalence of past-year medical and nonmedical cannabis use, and prescription opioid and tranquilizer/sedative use and misuse, according to the number of functional impairments reported. The adjusted odds of medical and nonmedical use or misuse of each substance in relation to any impairment, number of impairments, and specific impairments were estimated using logistic regression. Analyses were conducted in December 2020. Compared with those reporting no impairments, those reporting any impairment were more likely to report use of cannabis and (mis)use of prescription opioids and tranquilizers/sedatives (all p<0.05). Prevalence of (mis)use increased for each drug as number of impairments increased (all p<0.001). Having any impairment was associated with increased odds for medical cannabis use (AOR=2.28, 95% CI=1.57, 3.30) but not nonmedical use, and increased odds for misuse of prescription opioids (AOR=1.62, 95% CI=1.38, 1.91) and tranquilizers/sedatives (AOR=1.59, 95% CI=1.20, 2.11). Impaired thinking was associated with increased odds for use and misuse of each substance, and impaired ability to do errands was associated with increased odds for prescription opioid misuse (AOR=1.34, 95% CI=1.01, 1.78). Prescription drug misuse is linked to functional impairments among adults aged ≥50 years and may pose a potential risk for this vulnerable population.
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影响因子：
4.4
作者：
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通讯作者：
Nicholson, Harvey L.
影响因子：
4.1
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影响因子：
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DOI：
10.1016/j.ssmph.2017.12.005
发表时间：
2018-04
期刊：
SSM - population health
影响因子：
--
作者：
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通讯作者：
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影响因子：
6.3
作者：
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通讯作者：
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