COVID-19 vaccine hesitancy linked to increased internet search queries for side effects on fertility potential in the initial rollout phase following Emergency Use Authorization
COVID-19 vaccine hesitancy linked to increased internet search queries for side effects on fertility potential in the initial rollout phase following Emergency Use Authorization
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DOI：
10.1111/and.14156
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发表时间：
2021-06-28
期刊：
影响因子：
2.4
通讯作者：
Ramasamy, Ranjith
中科院分区：
文献类型：
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作者：
Diaz, Parris;Reddy, Pritika;Ramasamy, Ranjith
2020年12月11日COVID-19疫苗的紧急使用授权（EUA）因对未来生育力的潜在影响而受到质疑。我们假设，无论性别如何，在冠状病毒疫苗EUA后的48天内，与生育相关的查询将显著增加。我们寻求客观地识别互联网搜索查询中有关公众关注COVID-19疫苗对生育力的副作用（可能影响疫苗接种）的趋势。我们使用Google趋势调查了Google搜索引擎中与2020年10月24日至2021年1月27日期间冠状病毒疫苗和生育率相关的查询。查询次数最多的五个术语被确定为：“COVID疫苗生育力”、“COVID疫苗和不孕症”、“COVID疫苗不孕症”、“COVID疫苗生育力CDC”和“COVID 19疫苗不孕症”，分别增加了710.47%、207.56%、264.35%、2，943.7%和529.26%，所有p <0.001。这项研究表明，在2020年12月11日紧急使用授权（EUA）的同时，关于生育副作用的在线COVID-19疫苗相关查询有所增加。我们的研究结果客观地证明了人们对疫苗的关注度越来越高，并可能证明了疫苗接种犹豫的主要原因。未来的研究和对患者的咨询应有助于减轻这些担忧。
The Emergency Use Authorization (EUA) of the COVID-19 vaccine on December 11, 2020 has been met with hesitancy for uptake with some citing potential impacts on future fertility. We hypothesised that irrespective of sex, fertility-related queries would markedly increase during the 48 days following EUA of the coronavirus vaccine. We sought to objectively identify trends in internet search queries on public concerns regarding COVID-19 vaccine side effects on fertility that might impact vaccine uptake. We used Google Trends to investigate queries in Google's Search Engine relating to the coronavirus vaccine and fertility between 10/24/2020 and 1/27/2021. The five most queried terms were identified as: 'COVID Vaccine Fertility', 'COVID Vaccine and Infertility', 'COVID Vaccine Infertility', 'COVID Vaccine Fertility CDC', and 'COVID 19 Vaccine Infertility' with an increase of 710.47%, 207.56%, 264.35%, 2,943.7%, and 529.26%, respectively, all p < .001. This study indicates that there was an increase in online COVID-19 vaccine-related queries regarding fertility side effects coinciding with the Emergency Use Authorization (EUA) on December 11, 2020. Our results objectively evidence the increased concern regarding the vaccine and likely demonstrate a major cause for hesitancy in vaccine uptake. Future studies and counselling with patients should be undertaken to help mitigate these concerns.