[Subcellular localization of ataxin-3 and its effect on the morphology of cytoplasmic organoids].

[Subcellular localization of ataxin-3 and its effect on the morphology of cytoplasmic organoids].
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ataxin-3的亚细胞定位及其对细胞质类器官形态的影响

DOI:
10.3760/cma.j.issn.1003-9406.2015.03.011
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发表时间:
2015-06
期刊:
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
影响因子:
--
通讯作者:
Tang, Jianguang
Tang, Jianguang
中科院分区:
其他
文献类型:
--
作者:
Zhang, Hainan;Wang, Chunyu;Dai, Heping;Tang, Jianguang

文献摘要

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目的探讨ataxin-3的亚细胞定位及聚谷氨酰胺(polyQ)扩增突变对线粒体、高尔基体和内质网形态的影响。方法采用瞬时转染法构建
OBJECTIVE To explore the subcellular localization of ataxin-3 and the effect of polyglutamine (polyQ) expansion mutation on the morphology of mitochondrion, golgi apparatus and endoplasmic reticulum. METHODS Transient transfection was employed to build