Photocatalytic Defluorinative Three-Component Reaction of α-Trifluoromethyl Alkenes, Alkenes, and Sodium Sulfinates: Synthesis of Monofluorocyclopentenes
Photocatalytic Defluorinative Three-Component Reaction of α-Trifluoromethyl Alkenes, Alkenes, and Sodium Sulfinates: Synthesis of Monofluorocyclopentenes
复制标题
α-三氟甲基烯烃、烯烃和亚磺酸钠的光催化脱氟三组分反应：单氟环戊烯的合成
DOI：
10.1021/acs.orglett.2c02202
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发表时间：
2022-08-04
期刊：
影响因子：
5.2
通讯作者：
Zhou, Lei
中科院分区：
文献类型：
--
作者：
Li, Weiyu;Chen, Xiaofei;Zhou, Lei
A photocatalytic three-component reaction of alpha- trifluoromethyl alkenes, electron-rich alkenes, and sodium sulfinates for the synthesis of gem-difluoroalkenes in a radical/ polar crossover manner was developed. Due to the strong electron-withdrawing nature of the sulfonyl group, the resultant gem-difluoroalkenes can be converted into various monofluorocyclo-pentenes via intramolecular base-mediated SNV reactions in one pot.
