Paediatric intraoral mucoepidermoid carcinoma mimicking a bone lesion

Paediatric intraoral mucoepidermoid carcinoma mimicking a bone lesion
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DOI:
10.1111/j.1365-263x.2006.00770.x
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发表时间:
2007-03-01
影响因子:
3.8
通讯作者:
Alves, Fabio
Alves, Fabio
中科院分区:
医学3区
文献类型:
--
作者:
Moraes, Paulo;Pereira, Claudio;Alves, Fabio

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背景。唾液腺粘液表皮样癌最常见于成人的五、六十岁。虽然不常见,但它是儿童,特别是青少年的主要恶性唾液腺肿瘤。病例报告。一个14岁的女孩在她的上颚有一个肿块,已经持续了一年。在全景x线上,在左侧上颌窦区观察到一界限清晰的放射透光区。最初的临床诊断假设是中央巨细胞肉芽肿。进行了切口活检,最终的显微镜诊断为粘液表皮样癌。经广泛经口切除肿瘤,患者无症状4年。黏液表皮样癌在儿科患者中并不常见,但在儿童口腔黏膜下肿块/结节的鉴别诊断中必须考虑到它,特别是在上颚。
Background. Mucoepidermoid carcinoma of the salivary glands occurs most frequently in adults during the fifth and sixth decades of life. Although uncommon, it is the main malignant salivary gland tumour in children, particularly adolescents.Case report. A 14-year-old girl presented with a mass in her palate that had had a duration of one year. On panoramic X-ray, a well-delimited radiolucent area was observed on the left maxillary sinus region. The initial clinical diagnostic hypothesis was that this was a central giant cell granuloma. An incisional biopsy was performed and the final microscopic diagnosis was mucoepidermoid carcinoma. The tumour was removed by a wide transoral resection and the patient has been asymptomatic for 4 years.Conclusion. Mucoepidermoid carcinoma in paediatric patients is uncommon, but it must be considered in differential diagnoses of intraoral submucosal mass/nodules in children, particularly in the palate.