Novel developments on cervical length screening and progesterone for preventing preterm birth
Novel developments on cervical length screening and progesterone for preventing preterm birth
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DOI：
10.1111/j.1471-0528.2008.02008.x
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发表时间：
2009-01-01
影响因子：
5.8
通讯作者：
Berghella, V.
中科院分区：
文献类型：
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作者：
Berghella, V.
经阴道超声测量宫颈长度（CL）是预防早产（PTB）的有效筛查试验。CL均符合有效筛选试验的标准。它研究了一种重要的疾病（PTB）;它是安全的，99%以上的女性可以接受;它认识到PTB之前许多周的早期无症状阶段;它具有良好的描述技术，可重复性，到目前为止在所有人群研究中预测PTB;而且，也许最重要的是，它已经表明“早期”治疗在预防方面是有效的。这两种干预措施仅对特定人群有效，即超声指示的环扎术和阴道孕酮。
Cervical length (CL) measured by transvaginal ultrasound is an effective screening test for the prevention of preterm birth (PTB). The criteria for an effective screening test are all met by CL. It studies an important condition (PTB); it is safe and acceptable by > 99% of women; it recognises an early asymptomatic phase that precedes PTB by many weeks; it has a well-described technique, is reproducible, is predictive of PTB in all populations studies so far; and, perhaps most importantly, it has been shown that 'early' treatment is effective in prevention. These two interventions, effective only in specific populations, are ultrasound-indicated cerclage and vaginal progesterone.