Proton Pump Inhibitors and Hypomagnesemia in the General Population: A Population-Based Cohort Study
Proton Pump Inhibitors and Hypomagnesemia in the General Population: A Population-Based Cohort Study
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DOI：
10.1053/j.ajkd.2015.05.012
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发表时间：
2015-11-01
影响因子：
13.2
通讯作者：
Hoorn, Ewout J.
中科院分区：
文献类型：
--
作者：
Kieboom, Brenda C. T.;Kiefte-de Jong, Jessica C.;Hoorn, Ewout J.
Background: Proton pump inhibitor (PPI) use has been associated with hypomagnesemia in case reports and hospital-based cohort studies. Our objective was to determine whether PPI use is associated with hypomagnesemia in the general population and whether this is also found in histamine 2 receptor antagonist (H2RA) users.Study Design: Prospective cohort study.Setting & Participants: 9,818 individuals from the general population (Rotterdam Study).Predictor: PPI use and H2RA use compared to no use.Outcomes & Measurements: Serum magnesium and hypomagnesemia (serum magnesium
