Thrombotic thrombocytopenia due to SARS-CoV-2 vaccination.

Thrombotic thrombocytopenia due to SARS-CoV-2 vaccination.
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DOI:
10.3949/ccjm.88a.ccc078
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发表时间:
2021-05-06
影响因子:
6.1
通讯作者:
McCrae, Keith R
McCrae, Keith R
中科院分区:
医学4区
文献类型:
--
作者:
McCrae, Keith R

文献摘要

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疫苗诱导的血栓性血小板减少症(VITT)在接种AztraZeneca ChAdOx1nCoV-19和Johnson and Johnson AD26后被报道。COV2.S疫苗。这份手稿简要概述了报告的病例、临床和实验室特征,以及目前对VITT发病机制的了解。作者还提出了一些尚未回答的问题,并指出了未来研究的方向。
Vaccine-induced thrombotic thrombocytopenia (VITT) has been reported after vaccination with the AztraZeneca ChAdOx1 nCoV-19 and the Johnson and Johnson Ad26. COV2.S vaccines. This manuscript provides a brief overview of reported cases, clinical and laboratory features, and current understanding of the pathogenesis of VITT. The author also poses unananswered questions and identifies directions for future study.