Relation between Nasal and Middle Ear Allergy Experimental Study
Relation between Nasal and Middle Ear Allergy Experimental Study
复制标题
鼻与中耳过敏实验研究的关系
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
T. Kumazawa
中科院分区：
文献类型：
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作者：
T. Yamashita;N. Okazaki;T. Kumazawa
本研究旨在阐明鼻变态反应与渗出性中耳炎的关系，并观察动物咽鼓管自身的变态反应性改变。将抗原导入致敏豚鼠的鼓室后，在组织学上可清楚地观察到咽鼓管和鼓室的过敏性变化。另一方面，鼻内给予抗原在鼻和咽部产生明显的过敏性变化，但在咽鼓管或鼓室中没有变化。鉴于这些发现，我们认为鼻变态反应与中耳和咽鼓管的变态反应没有直接关系。
This study was undertaken to clarify the relation between nasal allergy and otitis media with effusion and to observe histologically the allergic changes in the eustachian tube itself in animals. Allergic changes in the eustachian tube and tympanic cavity were clearly observed histologically when the antigen had been introduced into the tympanic cavity of sensitized guinea pigs. On the other hand, administration of the antigen into the nose produced marked allergic changes in the nose and pharynx but no change in the eustachian tube or tympanic cavity. In view of these findings, it is suggested that allergy of the nose bears little direct relation to that of the middle ear and the eustachian tube.