Decolonization of children after incision and drainage for MRSA abscess: a retrospective cohort study.
Decolonization of children after incision and drainage for MRSA abscess: a retrospective cohort study.
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MRSA 脓肿切开引流后儿童的去定植：一项回顾性队列研究。
DOI：
10.1177/0009922814556059
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发表时间：
2015
影响因子：
1.6
通讯作者：
Downs,StephenM
中科院分区：
文献类型：
--
作者：
Finnell,SMariaE;Rosenman,MarcB;Christenson,JohnC;Downs,StephenM
背景/目的。耐甲氧西林金黄色葡萄球菌 (MRSA) 脓肿切开引流 (I&D) 后去定植是否会减少儿童重复 I&D 和 MRSA 阳性培养物尚不清楚。材料/方法。对符合条件的儿童（2003-2010 年）确定转诊至儿科传染病服务中心 (PIDS) 进行非殖民化，并对结果进行了超过 12 个月的研究。结果。我们确认了 653 名儿童； PIDS 已发现 54 个。在 PIDS 组中，没有患者（0/54，0%）重复进行 I&D。在无 PIDS 组中，36/599 (6%) 进行了重复 I&D，P= 0.06。重复 I&D 的逻辑回归模型显示没有显着影响，比值比 = 0.29； 95% 置信区间 = 0.04-2.15；P= .23。在 PIDS 组中，3 名患者（3/54，5.6%）重复 MRSA 阳性培养。在无 PIDS 组中，58/599 (9.7%) 的重复培养呈阳性，P= .46。阳性培养物的逻辑回归模型显示没有显着影响（比值比 = 0.55；95% 置信区间 = 0.17-1.81；P= .32）。结论。我们发现去定植与重复 I&D 或 MRSA 阳性培养之间没有统计学上的显着关联。
Background/Purpose. Whether decolonization following incision and drainage (I&D) for methicillin-resistantStaphylococcus aureus(MRSA) abscess decreases repeat I&D and MRSA-positive cultures in children is unknown.Materials/Methods. Referral to the Pediatric Infectious Disease Service (PIDS) for decolonization was determined for eligible children (2003-2010), with outcomes studied over 12 months.Results. We identified 653 children; 54 had been seen by PIDS. In the PIDS group, no patients (0/54, 0%) had a repeat I&D. In the no PIDS group 36/599 (6%) had a repeat I&D,P= .06. Logistic regression modeling for repeat I&D showed no significant effect, odds ratio = 0.29; 95% confidence interval = 0.04-2.15;P= .23. In the PIDS group, 3 patients (3/54, 5.6%) had a repeat MRSA-positive culture. In the no PIDS group, 58/599 (9.7%) had a positive repeat culture,P= .46. Logistic regression modeling for positive culture showed no significant effect (odds ratio = 0.55; 95% confidence interval = 0.17-1.81;P= .32).Conclusions. We detected no statistically significant association between decolonization and repeat I&D or MRSA-positive culture.