Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial
Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial
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DOI：
10.3899/jrheum.141129
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发表时间：
2015-07-01
影响因子：
3.9
通讯作者：
Bartlett, Susan J.
中科院分区：
文献类型：
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作者：
Moonaz, Steffany Haaz;Bingham, Clifton O., III;Bartlett, Susan J.
Objective.评价以整体为基础的哈达瑜伽对关节炎患者久坐不动的效果。有75名18岁以上的久坐不动的类风湿性关节炎（RA）或膝关节骨关节炎的成年人被随机分配到8周的瑜伽（两个60分钟的课程和1个家庭练习/周）或候补名单。姿势根据个人需要进行了修改。主要终点是根据基线调整的身体健康[医学结局研究简表-36（SF-36）身体成分总结（PCS）];探索性调整结局包括健身、情绪、压力、自我效能、SF-36健康相关生活质量（HRQOL）和RA疾病活动。在每个完成瑜伽的人中，我们探索了9个月的长期影响。参与者大多为女性（96%）、白色（55%）和受过大学教育（51%），平均（SD）年龄为52岁（12岁）。平均病程为9年，49%患有RA。在第8周，瑜伽与显著较高的PCS（6.5，95% CI 2.0-10.7），步行能力（125 m，95% CI 15-235），积极情感（5.2，95% CI 1.4-8.9）和较低的流行病学研究中心抑郁量表（-3.0，95% CI -4.8 - -1.3）相关。SF-36角色生理、疼痛、一般健康、活力和心理健康量表明显改善（p < 0.05）。两组之间的平衡、握力和灵活性相似。在等待名单中的28人中，有22人完成了瑜伽。在所有瑜伽参与者中，在8周时观察到平均PCS，灵活性，6分钟步行，所有心理和大多数HRQOL领域的显着改善（p < 0.05），9个月后仍然明显。7例不良事件中，无一例与瑜伽相关。初步证据表明，瑜伽可以帮助久坐不动的关节炎患者安全地增加身体活动，改善身心健康和HRQOL。临床试验NCT 00349869。
Objective. To evaluate the effect of Integral-based hatha yoga in sedentary people with arthritis.Methods. There were 75 sedentary adults aged 18+ years with rheumatoid arthritis (RA) or knee osteoarthritis randomly assigned to 8 weeks of yoga (two 60-min classes and 1 home practice/wk) or waitlist. Poses were modified for individual needs. The primary endpoint was physical health [Medical Outcomes Study Short Form-36 (SF-36) physical component summary (PCS)] adjusted for baseline; exploratory adjusted outcomes included fitness, mood, stress, self-efficacy, SF-36 health-related quality of life (HRQOL), and RA disease activity. In everyone completing yoga, we explored longterm effects at 9 months.Results. Participants were mostly female (96%), white (55%), and college-educated (51%), with a mean (SD) age of 52 years (12 yrs). Average disease duration was 9 years and 49% had RA. At 8 weeks, yoga was associated with significantly higher PCS (6.5, 95% CI 2.0-10.7), walking capacity (125 m, 95% CI 15-235), positive affect (5.2, 95% CI 1.4-8.9), and lower Center for Epidemiologic Studies Depression Scale (-3.0, 95% CI -4.8 - -1.3). Significant improvements (p < 0.05) were evident in SF-36 role physical, pain, general health, vitality, and mental health scales. Balance, grip strength, and flexibility were similar between groups. Twenty-two out of 28 in the waitlist group completed yoga. Among all yoga participants, significant (p < 0.05) improvements were observed in mean PCS, flexibility, 6-min walk, and all psychological and most HRQOL domains at 8 weeks with most still evident 9 months later. Of 7 adverse events, none were associated with yoga.Conclusion. Preliminary evidence suggests yoga may help sedentary individuals with arthritis safely increase physical activity, and improve physical and psychological health and HRQOL. Clinical Trials NCT00349869.