Comparison of Red and Infrared Low-level Laser Therapy in the Treatment of Acne Vulgaris.
Comparison of Red and Infrared Low-level Laser Therapy in the Treatment of Acne Vulgaris.
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DOI：
10.4103/0019-5154.94283
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发表时间：
2012-03
影响因子：
1.7
通讯作者：
Djavid GE
中科院分区：
文献类型：
--
作者：
Aziz-Jalali MH;Tabaie SM;Djavid GE
寻常痤疮是一种非常普遍的皮肤病，并且仍然是实践中的一个主要问题。最近，已使用各种光谱的光疗来治疗痤疮。有一些证据表明低强度激光疗法（LLLT）在治疗痤疮皮损方面具有有益效果。在本研究中，评估了两种不同波长的 LLLT（630 和 890 nm）对寻常痤疮的治疗效果。这项研究是一项单盲随机临床试验。年龄超过 18 岁的轻至中度寻常痤疮患者分别在面部左右两侧接受红色 LLLT（630 nm）和红外 LLLT（890 nm）治疗，每周两次，共 12 个疗程，并在基线和第 2、4、6 和 8 周进行临床评估。 28 名患者参与了这项研究。治疗10周后，630 nm LLLT治疗侧痤疮皮损明显减少（27.7±12.7至6.3±1.9）（P<0.001），但890 nm LLLT治疗侧痤疮皮损的减少不显着（26.9±12.4至22.2±8.5）（P>0.05）。与红外波长相比，红色波长用于 LLLT 治疗寻常痤疮是安全有效的。
Acne vulgaris is a very prevalent skin disorder and remains a main problem in practice. Recently, phototherapy with various light spectrums for acne has been used. There are some evidences that low-level laser therapy (LLLT) has beneficial effect in the treatment of acne lesions. In this study, two different wavelengths of LLLT (630 and 890 nm) were evaluated in treatment of acne vulgaris. This study was a single-blind randomized clinical trial. Patients with mild to moderate acne vulgaris and age above 18 years and included were treated with red LLLT (630 nm) and infrared LLLT (890 nm) on the right and left sides of the face respectively, twice in a week for 12 sessions, and clinically assessed at baseline and weeks 2, 4, 6, and 8. Twenty-eight patients were participated in this study. Ten weeks after treatment acne lesion were significantly decreased in the side treated by 630 nm LLLT (27.7±12.7 to 6.3±1.9) (P<0.001), but this decrease was not significant in the site treated by 890 nm LLLT (26.9±12.4 to 22.2±8.5) (P>0.05). Red wavelength is safe and effective to be used to treat acne vulgaris by LLLT compared to infrared wavelength.