Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective
Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective
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DOI：
10.1039/c1sc00368b
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发表时间：
2011-01-01
期刊：
影响因子：
8.4
通讯作者：
Hu, Xile
中科院分区：
文献类型：
--
作者：
Hu, Xile
非活化卤代烷的交叉偶联是有机合成中潜在的变革性方法。本文综述了近年来镍催化非活化卤代烷偶联反应的研究进展。这些耦合反应的机制目前的理解是突出的。由于该机制是配体依赖性的，因此根据催化中使用的配体类型来组织视角。
Cross coupling of non-activated alkyl halides is a potentially transformative methodology in organic synthesis. Herein we review the recent development of nickel-catalyzed coupling of non-activated alkyl halides. The current understanding of the mechanism of these coupling reactions is highlighted. As the mechanism is ligand-dependant, the perspective is organized according to the types of ligands employed in the catalysis.