ATTENUATED BLOOD CORTICOSTERONE RHYTHM IN RATS WITH JEJUNAL RESECTION
ATTENUATED BLOOD CORTICOSTERONE RHYTHM IN RATS WITH JEJUNAL RESECTION
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DOI：
10.1016/0024-3205(84)90620-9
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发表时间：
1984-01-01
期刊：
影响因子：
6.1
通讯作者：
SHIMAZU, T
中科院分区：
文献类型：
--
作者：
KATO, H;SAITO, M;SHIMAZU, T
本文研究了大鼠空肠或回肠切除后血皮质酮浓度的昼夜节律变化。回肠切除大鼠的皮质酮节律正常，自由进食时皮质酮节律在黑暗期开始时达到峰值，而在光照期限制进食时间时，皮质酮节律的相位发生了变化。空肠切除大鼠也表现出类似的皮质酮节律，但其幅度低于回肠切除大鼠。两组大鼠的体重和血尿素浓度的昼夜节律无差异。空肠显然是一个重要的部位，在那里食物的感觉被接收为皮质酮节律的夹带信号。
Circadian rhythmic changes in blood corticosterone concentration were studied in rats after resection of the jejunum or the ileum. The rats with ileal resection showed a normal corticosterone rhythm, which a peak at the beginning of the dark period when they were fed ad libitum, and the phase of the rhythm shifted when the feeding time was restricted to a specific time of day during the light period. The rats with jejunal resection also showed a similar corticosterone rhythm, but its amplitude was lower compared to that of the rats with ileal resection. There were no differences in body weight and the circadian rhythm of blood urea concentration between 2 groups of rats. The jejunum apparently is an important site where the sense of food is received as an entraining signal for the corticosterone rhythm.