User-initialized active contour segmentation and golden-angle real-time cardiovascular magnetic resonance enable accurate assessment of LV function in patients with sinus rhythm and arrhythmias.
User-initialized active contour segmentation and golden-angle real-time cardiovascular magnetic resonance enable accurate assessment of LV function in patients with sinus rhythm and arrhythmias.
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DOI：
10.1186/s12968-015-0146-9
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发表时间：
2015-05-21
期刊：
影响因子：
--
通讯作者：
Han Y
中科院分区：
文献类型：
--
作者：
Contijoch F;Witschey WR;Rogers K;Rears H;Hansen M;Yushkevich P;Gorman J 3rd;Gorman RC;Han Y
在心律失常期间获得的数据保留在实时心血管磁共振（rt-CMR）中，但有有限且不一致的证据表明rt-CMR可以准确评估左心室（LV）功能或心律失常期间的心跳间变化。收集了22例临床患者（18例窦性心律和4例心律失常患者）的多层短轴电影和实时黄金角径向CMR数据。通过与临床上可接受的软件上的手动分割进行比较，对用户初始化的主动轮廓分割（ACS）软件进行了确认。对于2D采集中的每张图像，计算切片体积，并通过使用多个切片对LV求和来估计全局LV体积。使用不同的图像曝光时间和帧速率重建实时成像数据，以评估时间分辨率对ACS每个切片中测量功能的影响。最后，使用ACS测量心律失常患者异位和非异位搏动的整体容积功能。ACS提供全局LV容积测量，与窦性心律患者回顾性门控电影图像的手动量化无显著差异。曝光时间为95.2 ms，帧速率> 89帧/秒，黄金角实时成像可在患者心率范围内准确捕获血流动力学功能。在4例频繁异位收缩的患者中，初步量化了异位搏动对血流动力学功能的影响。用户初始化的活动轮廓和黄金角实时径向CMR可用于确定患者随时间变化的LV功能。这些方法对评价频繁心律失常患者的左室功能非常有用。
Data obtained during arrhythmia is retained in real-time cardiovascular magnetic resonance (rt-CMR), but there is limited and inconsistent evidence to show that rt-CMR can accurately assess beat-to-beat variation in left ventricular (LV) function or during an arrhythmia. Multi-slice, short axis cine and real-time golden-angle radial CMR data was collected in 22 clinical patients (18 in sinus rhythm and 4 patients with arrhythmia). A user-initialized active contour segmentation (ACS) software was validated via comparison to manual segmentation on clinically accepted software. For each image in the 2D acquisitions, slice volume was calculated and global LV volumes were estimated via summation across the LV using multiple slices. Real-time imaging data was reconstructed using different image exposure times and frame rates to evaluate the effect of temporal resolution on measured function in each slice via ACS. Finally, global volumetric function of ectopic and non-ectopic beats was measured using ACS in patients with arrhythmias. ACS provides global LV volume measurements that are not significantly different from manual quantification of retrospectively gated cine images in sinus rhythm patients. With an exposure time of 95.2 ms and a frame rate of > 89 frames per second, golden-angle real-time imaging accurately captures hemodynamic function over a range of patient heart rates. In four patients with frequent ectopic contractions, initial quantification of the impact of ectopic beats on hemodynamic function was demonstrated. User-initialized active contours and golden-angle real-time radial CMR can be used to determine time-varying LV function in patients. These methods will be very useful for the assessment of LV function in patients with frequent arrhythmias.
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影响因子：
19.7
作者：
Kühl, HP;Spuentrup, E;Buecker, A
通讯作者：
Buecker, A
影响因子：
3.3
作者：
Saybasili, Haris;Derbyshire, J. Andrew;Seiberlich, Nicole
通讯作者：
Seiberlich, Nicole
DOI：
10.1186/1532-429x-15-79
发表时间：
2013-09-12
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Voit D;Zhang S;Unterberg-Buchwald C;Sohns JM;Lotz J;Frahm J
通讯作者：
Frahm J
DOI：
10.1109/34.537343
发表时间：
1996-09-01
影响因子：
23.6
作者：
Zhu, SC;Yuille, A
通讯作者：
Yuille, A
影响因子：
6.4
作者：
Boll, DT;Merkle, EM;Lewin, JS
通讯作者：
Lewin, JS