The accuracy of extracted target motion trajectories in four-dimensional cone-beam computed tomography for lung cancer patients
The accuracy of extracted target motion trajectories in four-dimensional cone-beam computed tomography for lung cancer patients
复制标题
DOI：
10.1016/j.radonc.2016.07.022
复制
发表时间：
2016-10-01
影响因子：
5.7
通讯作者：
Kanno, Ikuo
中科院分区：
文献类型：
--
作者：
Iramina, Hiraku;Nakamura, Mitsuhiro;Kanno, Ikuo
目的：将双源四维锥束计算机断层扫描(4D-CBCT)中提取的靶点运动轨迹与4D-CBCT同时获得的实际三维(3D)靶点运动轨迹进行对比，以量化提取的靶点运动轨迹的准确性。材料和方法：对19种不同的正弦样形态和13例植入标志物的肺癌患者进行了4D-CBCT扫描。使用基于幅度(Amp)或相位(Ph)的内部(In)或外部(Ex)替代物进行重建。靶点分别是假性肿瘤和植入的标记物，用于模体和临床研究。通过确定在每个第i个阶段(0)中从4D-CBCT提取的3D目标位置与通过透视检测的实际3D目标位置之间的最大误差(Maxe(I))来评估精度
Purpose: To quantify the accuracy of extracted target motion trajectories in dual-source four-dimensional cone-beam computed tomography (4D-CBCT) by comparison with the actual three-dimensional (3D) target motion acquired simultaneously during 4D-CBCT scan.Materials and methods: 4D-CBCT scans were performed for 19 different sinusoidal-like patterns and 13 lung cancer patients with implanted markers. Internal (In) or external (Ex) surrogates with amplitude (Amp)- or phase (Ph)-based sorting were used for the reconstructions. The targets were a pseudo-tumor and implanted marker for the phantom and clinical studies, respectively. The accuracy was evaluated by determining the maximum error (MaxE(i)) between the 3D target position extracted from 4D-CBCT and the actual 3D target position detected by fluoroscopy in each ith phase (0