Disseminated cutaneous and visceral Kaposi’s sarcoma in a patient with rheumatoid arthritis receiving corticosteroids and tacrolimus

Disseminated cutaneous and visceral Kaposi’s sarcoma in a patient with rheumatoid arthritis receiving corticosteroids and tacrolimus
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接受皮质类固醇和他克莫司治疗的类风湿性关节炎患者出现播散性皮肤和内脏卡波西肉瘤

DOI:
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发表时间:
2011
影响因子:
2.2
通讯作者:
S. Sato
S. Sato
中科院分区:
医学3区
文献类型:
--
作者:
Takashi Taniguchi;Y. Asano;M. Kawaguchi;A. Kogure;H. Mitsui;M. Sugaya;S. Sato

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卡波西肉瘤(KS)是一种具有低度恶性潜能的血管病变,由地理、遗传、环境和免疫因素之间复杂的相互作用引起。我们最近经历了一例罕见的 KS 病例,该病例与类风湿性关节炎相关,患者接受皮质类固醇和他克莫司治疗; KS 表现出异常激进的临床行为。我们在此报告临床病程的详细信息,并讨论皮质类固醇和他克莫司对本病例侵袭性 KS 发展的可能贡献。
Kaposi’s sarcoma (KS) is a vascular lesion of low-grade malignant potential caused by the complex interactions between geographic, genetic, environmental, and immunological factors. We recently experienced a rare case of KS associated with rheumatoid arthritis in a patient receiving corticosteroids and tacrolimus; the KS demonstrated unusually aggressive clinical behavior. We herein report the details of the clinical course and discuss the possible contribution of corticosteroids and tacrolimus to the development of aggressive KS in the present case.
DOI: 10.1158/0008-5472.can-07-6603
发表时间: 2008-07-15
期刊: CANCER RESEARCH
影响因子: 11.2
作者:
Basu, Aninda;Contreras, Alan G.;Datta, Dipak;Flynn, Evelyn;Zeng, Liling;Cohen, Herbert T.;Briscoe, David M.;Pal, Soumitro
通讯作者: Pal, Soumitro