Congenital Heart Disease After the Fukushima Nuclear Accident: The Japan Cardiovascular Surgery Database Study.
Congenital Heart Disease After the Fukushima Nuclear Accident: The Japan Cardiovascular Surgery Database Study.
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DOI：
10.1161/jaha.119.014787
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发表时间：
2020-07-07
影响因子：
5.4
通讯作者：
Okita Y
中科院分区：
文献类型：
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作者：
Hirata Y;Shimizu H;Kumamaru H;Takamoto S;Motomura N;Miyata H;Okita Y
2011年3月，福岛第一核电站灾难对日本北部东北地区造成辐射损害。由此对怀孕母亲和新生儿造成的伤害令人担忧。我们使用日本心血管外科数据库对 2010 年至 2013 年期间先天性心脏病的发病率进行了基于登记的分析。我们选择了2010年1月1日至2013年12月31日之间出生的患有复杂先天性心脏病的接受手术的患者，并评估了2岁及以下患者按出生年份随时间推移的首次手术数量的趋势。 2010年至2013年出生年份首次手术数量分别为2978例、2924例、3077例和2940例，没有发现增加的趋势。此外，用每个出生月份的日本出生总数除以病例数，也没有发现逐年增加的趋势。针对复杂疾病（通常涉及多次后续手术）进行的首次手术的死亡率从 2010 年的 4.7% 下降到 2013 年的 2.2%。我们的分析显示，2010 年至 2013 年期间，先天性心脏病患者数量没有增加。之前的报告中福岛第一核电站灾难后手术总数逐年增加，可以解释为复杂疾病首次手术死亡率的下降。案例。仅用每年手术总数的增加来说明核灾难对先天性心脏病发病率的影响是一个过于简单化和危险的主张。
In March 2011, the Fukushima Daiichi nuclear power plant disaster inflicted radiation damage across the Tohoku region of Northern Japan. The consequent harm to pregnant mothers and newborns was a matter of concern. We performed a registry‐based analysis of the incidence of congenital heart disease during 2010 to 2013 using the Japan Cardiovascular Surgery Database. We selected patients who had complex congenital heart disease and who were born between January 1, 2010 and December 31, 2013 undergoing surgery, and assessed the trend in the number of first‐time surgeries performed for patients aged 2 years and younger by birth year over time. The numbers of first‐time surgeries for birth years 2010 to 2013 were 2978, 2924, 3077, and 2940, and no increasing trend was detected. Additionally, no increasing yearly trend was detected when the number of cases was divided by the total number of births in Japan in each birth month. The mortality of first‐time surgeries performed for complex diseases, which often involves multiple subsequent surgeries, decreased from 4.7% in 2010 to 2.2% in 2013. Our analyses showed no increase in the number of patients with congenital heart disease during 2010 to 2013. The yearly increase in the total number of surgeries following the Fukushima Daiichi nuclear disaster in a previous report can be explained by the decline in the mortality of first‐time surgeries for complex cases. Such use of only the increase in the total yearly number of surgeries to claim the effects of a nuclear disaster on the incidence of congenital heart disease is a far too simplistic and dangerous proposition.