The role of the posterior ciliary body in the biosynthesis of vitreous humour
The role of the posterior ciliary body in the biosynthesis of vitreous humour
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DOI：
10.1038/sj.eye.6700199
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发表时间：
2002-07-01
期刊：
影响因子：
3.9
通讯作者：
Mayne, R
中科院分区：
文献类型：
--
作者：
Bishop, PN;Takanosu, M;Mayne, R
最近，一些研究小组发表了关于玻璃体液的起源和结构以及视网膜内界层（ILL）的新信息。这篇简短的文章概述了这些新信息。有人提出，玻璃体蛋白是来自几种不同的细胞类型与非色素睫状上皮的后半部分是突出的几个结缔组织大分子的表达。此外，一些基底膜大分子也由睫状体表达，并且随后可在Muller细胞表面组装以形成ILL。新的数据表明，非色素睫状体上皮的后半部分具有大量的分泌活性，并且可能在眼睛发育中起关键作用。
Recently, several groups have published new information regarding the origins and structure of the vitreous humour, and the inner limiting lamina (ILL) of the retina. This short article provides an overview of this new information. It is proposed that vitreous proteins are derived from several different cell types with the posterior half of the non-pigmented ciliary epithelium being prominent in the expression of several connective tissue macromolecules. In addition, some basement membrane macromolecules are also expressed by the ciliary body and may subsequently be assembled on the surface of the Muller cells to form the ILL. New data suggest that the posterior half of the non-pigmented ciliary epithelium has substantial secretory activity and is likely to play a pivotal role in eye development.