A longitudinal study of Lancefield group A streptococcus acquisitions by a group of young Dunedin schoolchildren.
A longitudinal study of Lancefield group A streptococcus acquisitions by a group of young Dunedin schoolchildren.
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对达尼丁一群年轻学童进行兰斯菲尔德 A 组链球菌感染的纵向研究。
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
N. Dickson
中科院分区：
文献类型：
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作者：
J. Tagg;N. Ragland;N. Dickson
配对的唾液和咽部培养物在27个月内从一组103名年轻的达尼丁学童中获得了9次，进行了β溶血性兰斯菲尔德A组链球菌检测。858例咽部培养物中约20%和5%的唾液培养物呈阳性。尽管59例（57.3%）受试者至少分离出一次A组链球菌，但在采集标本时仅检测到7例临床明显的A组链球菌性咽炎。这项研究表明，咽部收购的A组链球菌经常发生在一些年轻的学童。在没有感染临床症状的情况下携带少量A组链球菌是常见的，在10名儿童中，相同类型的A组链球菌在超过12个月的时间内从咽部培养物中持续回收。目前还不清楚为什么有些儿童似乎不那么容易获得A组链球菌，而其他人则发展严重的延迟后遗症，这些感染。
Paired saliva and pharyngeal cultures obtained on nine occasions over a 27-month period from a group of 103 young Dunedin schoolchildren were tested for beta haemolytic Lancefield group A streptococci. Approximately 20% of the 858 pharyngeal cultures and 5% of the saliva cultures were positive. Although group A streptococci were isolated at least once from 59 (57.3%) of the subjects, only seven cases of clinically apparent group A streptococcus pharyngitis were detected at the time of specimen taking. The study has shown that pharyngeal acquisitions of group A streptococci occur frequently in some young schoolchildren. Carriage of small numbers of group A streptococci in the absence of clinical symptoms of infection was common and in ten children the same type of group A streptococcus was consistently recovered from pharyngeal cultures over periods of more than 12 months. It remains unclear why some children do not seem to so readily acquire group A streptococci, while others develop serious delayed sequelae to these infections.