The Association of Low Hemoglobin Levels with IgA Nephropathy Progression: A Two-Center Cohort Study of 1,828 Cases

The Association of Low Hemoglobin Levels with IgA Nephropathy Progression: A Two-Center Cohort Study of 1,828 Cases
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DOI:
10.1159/000508770
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发表时间:
2020-08-01
影响因子:
4.2
通讯作者:
Chen, Hong-yu
Chen, Hong-yu
中科院分区:
医学3区
文献类型:
--
作者:
Zhu, Bin;Liu, Wen-hua;Chen, Hong-yu

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目的:探讨血红蛋白水平与IgA肾病(IgAN)进展的关系。方法:在1828例活检证实的IgAN患者的双中心队列中,我们研究了血红蛋白水平与全因死亡率或肾衰竭(定义为eGFR下降40%)或ESKD(定义为eGFR)的综合主要结局的关系
Aim:To investigate the relationship between hemoglobin levels and the progression of IgA nephropathy (IgAN).Methods:In a two-center cohort of 1,828 cases with biopsy-proven IgAN, we examined the association of hemoglobin levels with the primary outcome of a composite of all-cause mortality or kidney failure defined as a 40% decline in eGFR, or ESKD (defined as eGFR