Development and Validation of the Low Vision Severely Constricted Peripheral Eyesight (LV-SCOPE) Questionnaire.
Development and Validation of the Low Vision Severely Constricted Peripheral Eyesight (LV-SCOPE) Questionnaire.
复制标题
低视力周边视力严重受限 (LV-SCOPE) 问卷的开发和验证。
DOI：
10.1016/j.ajo.2023.08.014
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发表时间：
2023
影响因子：
4.2
通讯作者：
Carlozzi,NoelleE
中科院分区：
文献类型：
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作者：
Ehrlich,JoshuaR;Andrews,Chris;Kumagai,Abigail;Goldstein,Jenna;Jayasundera,KThiran;Stelmack,Joan;Massof,Robert;Lee,PaulP;Carlozzi,NoelleE
目的开发并验证一种新的患者报告结果（PRO）测量方法，以评估严重外周视野丧失（PFL）患者的视力相关功能。设计前瞻性结局测量开发/验证研究。方法采用定性访谈法编制127项问卷。Kellogg眼科中心招募了116名因色素性视网膜炎（RP）或青光眼而患有严重PFL的参与者，并完成了李克特量表的电话问卷调查。纳入的参与者的视野水平范围<20度（RP），或使用增强青光眼分期系统（青光眼）在视力较好的一只眼（或如果另一只眼的视力<20/200）中出现混合性或广泛性4至5期缺陷。采用探索性因子分析和Rasch模型对响应数据进行分析。剔除功能不佳的项目，采用验证性因子分析来确保量表的单维性，并对模型进行改装以产生最终的仪器。结果最终的低视力严重收缩周边视力（LV-SCOPE）问卷包含6个领域的53个项目：移动性、物体定位、物体识别、阅读、社会功能和技术。由于缺失程度高、因素负载低、内部一致性低、局部依赖性高、项目信息低、项目冗余或项目功能差异，有74个项目被删除。使用Rasch项目校准，可以计算出6个一维LV-SCOPE域的个人能力得分，且具有良好的重测稳定性。结论LV-SCOPE问卷对严重PFL患者的6个关键领域的视力相关功能提供了有效和可靠的测量。研究结果支持这种心理测量有效工具的临床应用。
PURPOSETo develop and validate a novel patient-reported outcome (PRO) measure to assess vision-related functioning in individuals with severe peripheral field loss (PFL).DESIGNProspective outcome measure development/validation study.METHODSA 127-item questionnaire was developed based on a prior qualitative interview study. A total of 116 participants with severe PFL due to retinitis pigmentosa (RP) or glaucoma were recruited at the Kellogg Eye Center and completed the Likert-scaled telephone-administered questionnaire. Included participants had a horizontal extent of their visual field <20 degrees (RP) or a mixed or generalized stage 4 to 5 defect using the Enhanced Glaucoma Staging System (glaucoma) in the better seeing eye (or in 1 eye if the fellow eye visual acuity was <20/200). Response data were analyzed using exploratory factor analysis and Rasch modeling. Poorly functioning items were eliminated, confirmatory factor analysis was used to ensure scale unidimensionality, and the model was refit to produce the final instrument.RESULTSThe final Low Vision Severely Constricted Peripheral Eyesight (LV-SCOPE) Questionnaire contains 53 items across 6 domains: mobility, object localization, object recognition, reading, social functioning, and technology. There were 74 items removed because of high missingness, poor factor loadings, low internal consistency, high local dependency, low item information, item redundancy, or differential item functioning. Using Rasch item calibrations, person ability scores could be calculated for each of the 6 unidimensional LV-SCOPE domains with good test–retest stability.CONCLUSIONSThe LV-SCOPE Questionnaire provides a valid and reliable measure of vision-related functioning across 6 key domains relevant to individuals with severe PFL. Findings support the clinical utility of this psychometrically valid instrument.