Visual and Vestibular Selectivity for Self-Motion in Macaque Posterior Parietal Area 7a
Visual and Vestibular Selectivity for Self-Motion in Macaque Posterior Parietal Area 7a
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DOI：
10.1093/cercor/bhy272
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发表时间：
2019-09-01
期刊：
影响因子：
3.7
通讯作者：
Angelaki, Dora E.
中科院分区：
文献类型：
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作者：
Avila, Eric;Lakshminarasimhan, Kaushik J.;Angelaki, Dora E.
在系统地改变视觉模拟（光流线索）或实际（前庭线索）自我运动的速度的同时，我们研究了后顶叶区7a神经元对被动旋转和平移自我运动刺激的反应。与一般认为7a区的反应主要是视觉反应相反，我们发现了前庭在自我运动处理中占主导地位的证据。只有一小部分神经元表现出视觉/前庭和线性/角度自我运动线索的多感觉收敛。这些发现表明，视觉与前庭、线性与角度的自我运动可能是独立的神经元群编码。神经反应以自运动幅度（即速度）衡量，但时间动态在种群中是不同的。对层流记录的分析显示，刺激诱导的（信号相关）和刺激独立的（噪声相关）刺激计数变异性的相关性在距离依赖性很强的情况下下降，这支持了神经元在运动的感觉表征方面是空间聚集的观点。单单元和多单元反应模式也相关，但没有观察到其他系统依赖于皮质层或柱。这些发现描述了猕猴大脑后顶叶区与海马体形成相连的线性和角度自我运动的可能独立的多模态神经编码。
We examined the responses of neurons in posterior parietal area 7a to passive rotational and translational self-motion stimuli, while systematically varying the speed of visually simulated (optic flow cues) or actual (vestibular cues) self-motion. Contrary to a general belief that responses in area 7a are predominantly visual, we found evidence for a vestibular dominance in self-motion processing. Only a small fraction of neurons showed multisensory convergence of visual/vestibular and linear/angular self-motion cues. These findings suggest possibly independent neuronal population codes for visual versus vestibular and linear versus angular self-motion. Neural responses scaled with self-motion magnitude (i.e., speed) but temporal dynamics were diverse across the population. Analyses of laminar recordings showed a strong distance-dependent decrease for correlations in stimulus-induced (signal correlation) and stimulus-independent (noise correlation) components of spike-count variability, supporting the notion that neurons are spatially clustered with respect to their sensory representation of motion. Single-unit and multiunit response patterns were also correlated, but no other systematic dependencies on cortical layers or columns were observed. These findings describe a likely independent multimodal neural code for linear and angular self-motion in a posterior parietal area of the macaque brain that is connected to the hippocampal formation.