STUDIES ON ANTIGENIC CHANGES AND STRAIN DIFFERENCES IN BABESIA-ARGENTINA INFECTIONS

STUDIES ON ANTIGENIC CHANGES AND STRAIN DIFFERENCES IN BABESIA-ARGENTINA INFECTIONS
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DOI:
10.1111/j.1751-0813.1973.tb06806.x
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发表时间:
1973-01-01
影响因子:
1.1
通讯作者:
CURNOW, JA
CURNOW, JA
中科院分区:
农林科学4区
文献类型:
--
作者:
CURNOW, JA

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利用寄生红细胞凝集试验表明,B。在一只动物中复发时收集的阿根廷寄生虫抗原性不同。当这些复发的寄生虫通过微小牛蜱传播时,它们恢复到被认为是菌株特异性的共同抗原类型。从B带菌者中分离到7株。阿根廷新南威尔士州的10头牛通过蜱传播给未感染的小牛,并对所得蜱传播寄生虫的抗原和抗血清进行交叉试验。在所有同源试验中均获得了高滴度,而异源试验除1例外均显示出不显著滴度。这表明寄生虫中存在多种菌株特异性抗原。
Use of parasitized erythrocyte agglutination test showed that B. argentina parasites collected at relapse in the one animal were antigenically different. When these relapse parasites were transmitted through Boophilus microplus, they reverted to a common antigenic type which was thought to be strain specific. Seven isolates collected from field carriers of B. argentina in New South Wales were transmitted by tick to uninfected calves, and antigens and antisera of the resulting tick-transmitted parasites were cross tested. High titres were obtained in all homologous tests while heterologous tests showed insignificant titres in all but one case. This indicated multiplicity of strain-specific antigens in the parasites.