The Impact of Intimal Tear Location and Partial False Lumen Thrombosis in Acute Type B Aortic Dissection
The Impact of Intimal Tear Location and Partial False Lumen Thrombosis in Acute Type B Aortic Dissection
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DOI：
10.1016/j.athoracsur.2016.05.020
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发表时间：
2016-12-01
影响因子：
4.6
通讯作者：
Leshnower, Bradley G.
中科院分区：
文献类型：
--
作者：
Girish, Apoorva;Padala, Muralidhar;Leshnower, Bradley G.
背景资料。部分假腔(FL)血栓形成是急性B型主动脉夹层(ATBAD)长期死亡率的危险因素。本研究对部分血栓形成和部分血栓形成的ATBAD模型的FL压力进行了研究。25条猪主动脉被用来制作五个ATBAD模型，这些模型连接到一个脉动的流环上。模型A到模型C的FL具有如下形态：模型A，单侧近端撕裂；模型B，单侧远侧撕裂；以及模型C，单侧近侧和单侧远侧撕裂。模型D和E有单个近端和远端撕裂，伴有部分FL血栓形成。D模型近端为FL闭塞，D为远端FL闭塞。在90~150 mm水压范围内测量真腔压(TL)和FL压。在模型A中，FL压力比TL压力高6毫米汞(p<；0.01)。在模型B中，FL压力比TL压力低10 mm Hg(p
Background. Partial false lumen (FL) thrombosis is a risk factor for long-term mortality in acute type B aortic dissection (ATBAD). This study investigates FL pressures in models of ATBAD with patent and partially thrombosed FL.Methods. Twenty-five porcine aortas were used to create five models of ATBAD that were connected to a pulsatile flow loop. Models A through C had a patent FL with the following morphologies: model A, single proximal tear; model B, single distal tear; and model C, single proximal and single distal tear. Models D and E had a single proximal and a single distal tear, with partial FL thrombosis. Model D had FL occlusion of the proximal tear, and model D had FL occlusion of the distal tear. True lumen (TL) and FL pressures were measured at 90 to 150 mm Hg.Results. In model A, FL pressures were 6 mm Hg higher than TL pressures (p < 0.01). In model B, FL pressures were 10 mm Hg lower than TL pressures (p