Usefulness of ultrasonographic markers of carotid atherosclerosis (intima-media thickness, unstable carotid plaques and severe carotid stenosis) for predicting presence and extent of coronary artery disease
Usefulness of ultrasonographic markers of carotid atherosclerosis (intima-media thickness, unstable carotid plaques and severe carotid stenosis) for predicting presence and extent of coronary artery disease
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DOI：
10.2459/jcm.0b013e32832e62fd
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发表时间：
2009-12-01
影响因子：
3
通讯作者：
Vassanelli, Corrado
中科院分区：
文献类型：
--
作者：
Cicorella, Nicola;Zanolla, Luisa;Vassanelli, Corrado
目的探讨颈动脉超声评价在预测冠状动脉疾病的存在和程度的连续series of patients.Design我们回顾性研究了1337例患者，其中冠状动脉造影和颈动脉超声进行了评估，从1995年至2005年。考虑颈动脉疾病的标志物，如内膜中层厚度大于0.90 mm，不稳定斑块和严重狭窄（>= 70%）。颈动脉风险评分定义为这些参数的总和。我们认为，受显着的冠状动脉疾病的患者至少有一个病变超过50%的主要分支的冠状动脉。结果颈动脉粥样硬化的标志物在一个，两个或三支冠状动脉疾病的患者成比例增加。在单因素分析中，内膜中层厚度大于0.90 mm与冠状动脉疾病的比值比为2.28（1.8-2.9）（P
Objective To investigate the usefulness of carotid ultrasound evaluation in predicting the presence and the extent of coronary artery disease in a consecutive series of patients.Design We examined retrospectively 1337 patients in whom both coronary angiography and carotid ultrasound were evaluated,from 1995 to 2005. Markers of carotid artery disease were considered, such as intima-media thickness more than 0.90 mm, unstable plaque and severe stenosis (>= 70%). Carotid risk score was defined as the sum of these parameters. We considered as affected by significant coronary artery disease those patients with at least one lesion more than 50% within the main branches of the coronary arteries.Results The markers of carotid atherosclerosis increased proportionally in patients with one-, two- or three-vessel coronary artery disease. At univariate analysis, intima-media thickness more than 0.90 mm was associated with an odds ratio of coronary artery disease of 2.28 (1.8-2.9) (P