Noninvasive brain stimulation in traumatic brain injury.
Noninvasive brain stimulation in traumatic brain injury.
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DOI：
10.1097/htr.0b013e318217df55
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发表时间：
2012-07
期刊：
影响因子：
--
通讯作者：
Pascual-Leone A
中科院分区：
文献类型：
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作者：
Demirtas-Tatlidede A;Vahabzadeh-Hagh AM;Bernabeu M;Tormos JM;Pascual-Leone A
在过去的几十年里，脑刺激技术不断发展，出现了更多无痛、无创脑刺激的新方法。尽管在各种耐药神经和精神疾病中使用无创脑刺激的临床试验数量不断增加，但评估其在创伤性脑损伤（TBI）中的诊断和治疗潜力的研究在很大程度上缺乏。这篇综述介绍了不同的无创脑刺激技术，这些技术可能在创伤性脑损伤中找到潜在的应用。我们涵盖了经颅磁刺激（TMS），经颅直流电刺激（tDCS），低水平激光治疗（LLLT）和经颅多普勒超声（TCD）技术。我们简要概述了迄今为止的研究，讨论了可能的作用机制，并在考虑将这些方法转化为临床应用时提出了一些注意事项。
Brain stimulation techniques have evolved in the last few decades with more novel methods capable of painless, noninvasive brain stimulation. While the number of clinical trials employing noninvasive brain stimulation continues to increase in a variety of medication-resistant neurological and psychiatric diseases, studies evaluating their diagnostic and therapeutic potential in traumatic brain injury (TBI) are largely lacking. This review introduces different techniques of noninvasive brain stimulation, which may find potential use in TBI. We cover transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), low-level laser therapy (LLLT) and transcranial doppler sonography (TCD) techniques. We provide a brief overview of studies to date, discuss possible mechanisms of action, and raise a number of considerations when thinking about translating these methods to clinical use.