Sleep-related disturbances and physical inactivity are independently associated with obesity in adults
Sleep-related disturbances and physical inactivity are independently associated with obesity in adults
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DOI：
10.1038/sj.ijo.0803663
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发表时间：
2007-11-01
影响因子：
4.9
通讯作者：
Harma, M.
中科院分区：
文献类型：
--
作者：
Fogelholm, M.;Kronholm, E.;Harma, M.
目的：研究成年人（>= 30岁）肥胖、缺乏运动和睡眠相关障碍（阻塞性睡眠呼吸暂停（OSA）、睡眠持续时间、伴随白天疲劳的睡眠障碍）之间的关系。14.8岁）和4264名妇女（56.4岁）。主要结果测量：因变量，测量：腰围（WC）和体重指数（BMI）。独立变量，从一个详细的采访/问卷：可能的OSA，其他睡眠相关的干扰，睡眠时间，类型和频率的休闲体育活动。年龄，心理健康，吸烟和教育作为潜在的混杂因素包括在分析中。结果：在男性中，OSA和缺乏体力活动增加腹部肥胖（WC >= 102 cm）的可能性。缺乏体力活动也会增加，但长时间（>= 9小时/天）睡眠会降低男性腹部超重（WC：94-101 cm）的可能性。在女性中，腹型肥胖（WC >= 88 cm）与OSA、中度睡眠相关障碍和缺乏体力活动呈正相关。在两种性别中，教育调节了年龄对腹部肥胖的影响。使用BMI作为因变量并没有改变模型获得的一般信息。此外，腹部肥胖被认为是一个独立的危险因素，也在多变量模型预测类别的组合睡眠时间和睡眠disturbs.Conclusions：睡眠时间和睡眠相关的障碍与肥胖，即使在控制OSA和身体活动不足。研究结果支持睡眠与肥胖之间恶性循环的假设。
Objective: To study relationships between obesity, physical inactivity and sleep-related disturbances (obstructive sleep apnea (OSA), sleep duration, sleep disturbances concomitant with daytime tiredness) in adults (>= 30 years).Design: Cross-sectional study with a random population sample.Participants: A total of 3377 men (mean age 52.3, s.d. 14.8, years) and 4264 women (56.4, s.d. 17.2, years).Main outcome measures: Dependent variables, measured: Waist circumference (WC) and body mass index (BMI). Independent variables, from a detailed interview/questionnaire: probable OSA, other sleep-related disturbances, sleep duration, type and frequency of leisure physical activity. Age, mental health, smoking and education were included in analyses as potential confounders.Results: In men, OSA and physical inactivity increased likelihood for abdominal obesity (WC >= 102 cm). Physical inactivity also increased, but long (>= 9 h/day) sleep decreased likelihood for abdominal overweight (WC: 94-101 cm) in men. In women, abdominal obesity (WC >= 88 cm) was associated positively with OSA, moderate sleep-related disturbances, and physical inactivity. Education modulated the influence of age on abdominal obesity in both genders. Using BMI as the dependent variable did not change the general information obtained by the model. In addition, abdominal obesity was found to be an independent risk factor also in multivariable models predicting categories of a combined sleep duration and sleep disturbances.Conclusions: Sleep duration and sleep-related disturbances are associated with obesity, even after controlling for OSA and physical inactivity. The results support the hypothesis of vicious circle between sleep and obesity.